Anti-SLC30A4 antibody | MyBioSource MBS177050 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-SLC30A4 antibody

catalog :

MBS177050

quantity :

0.1 mg

price :

315 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

image

image 1 :

Anti- SLC30A4 antibody, Western blotting. All lanes: Anti SLC30A4 at 0.5ug/ml. Lane 1: MCF-7 Whole Cell Lysate at 40ug. Lane 2: A549 Whole Cell Lysate at 40ug. Predicted bind size: 47KD. Observed bind size: 47KD

image 2 :

Anti- SLC30A4 antibody, IHC(P). IHC(P): Rat Pancreas Tissue

image 3 :

Anti- SLC30A4 antibody, IHC(P). IHC(P): Rat Gaster Tissue

product information

catalog number :

MBS177050

products type :

Antibody

products full name :

Anti-SLC30A4 antibody

products short name :

[SLC30A4]

products name syn :

[Zinc Transporter 4]

other names :

[Zinc transporter 4; Zinc transporter 4; zinc transporter 4; znT-4; solute carrier family 30 member 4; solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 member 4]

products gene name :

[SLC30A4]

other gene names :

[SLC30A4; SLC30A4; ZNT4; ZNT4; ZnT-4]

uniprot entry name :

ZNT4_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Reacts with: Human, Rat. Predicted to work with: Mouse

sequence length :

429

specificity :

No cross reactivity with other proteins.

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

app notes :

Western Blot:. Concentration: 0.1-0.5ug/ml. Tested Species: Hu. Predicted: Ms. Immunohistochemistry(Paraffin-embedded Section):. Concentration: 0.5-1ug/ml. Tested Species: Rat. Predicted: Species: Hu, Ms. Antigen Retrieval: By Heat. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20 mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC30A4 (407-427aa TIQLQSYRQEVDRTCANCQSS), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 . Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for Zinc transporter 4(SLC30A4) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: Zinc transporter 4, also called SLC30A4 or ZNT4 is a protein that in humans is encoded by the SLC30A4 gene. SLC30A4, or ZNT4 belongs to the ZNT family of zinc transporters. This gene is mapped to 15q21.1. Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases, alkaline phosphatases, various dehydrogenases, and superoxide dismutases. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop.

ncbi gi num :

206729947

ncbi acc num :

O14863.2

uniprot acc num :

O14863

ncbi summary :

Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008]

uniprot summary :

SLC30A4: Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family; Transporter. Chromosomal Location of Human Ortholog: 15q21.1 15q21.1. Cellular Component: late endosome; cytoplasm; integral to membrane; endosome membrane. Molecular Function: zinc ion transmembrane transporter activity. Biological Process: zinc ion homeostasis; response to toxin

size1 :

0.1 mg

price1 :

315 USD

more info or order :

MyBioSource product webpage