Anti-Calbindin Antibody | MyBioSource MBS176994 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-Calbindin Antibody

catalog :

MBS176994

quantity :

0.1 mg

price :

280 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS176994

products type :

Antibody

products full name :

Anti-Calbindin Antibody

products short name :

Calbindin

products name syn :

Calbindin; calbindin 1, 28kDa; avian-type antibody; CAB27 antibody; CALB 1 antibody; CALB antibody; CALB1 antibody; CALB1_HUMAN antibody; Calbindin 1 28kDa antibody; Calbindin antibody; Calbindin D28 antibody; D 28K antibody; D-28K antibody; D28K antibody; OTTHUMP00000166027 antibody; OTTHUMP00000225441 antibody; RTVL H protein antibody; Vitamin D dependent calcium binding protein antibody; Vitamin D dependent calcium binding protein avian type antibody; Vitamin D dependent calcium binding protein avian-type antibody; Vitamin D-dependent calcium-binding protein antibody

other names :

Calbindin; Calbindin; calbindin; D-28K; calbindin D28; RTVL-H protein; calbindin 1, (28kD); vitamin D-dependent calcium-binding protein, avian-type; calbindin 1, 28kDa; Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type

products gene name :

CALB1

other gene names :

CALB1; CALB1; CALB; CAB27

uniprot entry name :

CALB1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

261

specificity :

No cross reactivity with other proteins.

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

app notes :

Western Blot:. Concentration: 0.1-0.5ug/ml. Tested Species: Rat. Predicted Species: Hu. Antigen Retrieval: -. Immunohistochemistry (Paraffin-embedded Section) Concentration: 0.5-1 ug/ml. Tested Species: Hu, Ms, Rat. Predicted Species: -. Antigen Retrieval: By Heat. WB: The detection limit for Calbindin is approximately 0.25ng/lane under reducing conditions. Tested Species: in-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20 mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

other info1 :

Immunogen: E Coli-derived human Calbindin recombinant protein (Position: A2-E175). Human Calbindin shares 99% amino acid (aa) sequence identity with mouse and rat Calbindin.

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for Calbindin(CALB1) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: Calbindin is a calcium-binding protein belonging to the troponin C superfamily. Calretinin is expressed in central and peripheral nervous system and in many normal and pathological tissues. The rat and human calretinin exhibit 98% sequence homology and 91% homology to many other species. Two calcium binding proteins, calbindin and calretinin, have been reported to be expressed in abundance in Purkinje cells and other cell types in the cerebellum.

ncbi gi num :

115394

ncbi acc num :

P05937.2

uniprot acc num :

P05937

ncbi mol weight :

23,609 Da

ncbi pathways :

Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213307); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213276)

ncbi summary :

Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted. [provided by RefSeq, Jul 2008]

uniprot summary :

CALB1: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3 ,5 -cyclic nucleotide phosphodiesterase. Interacts with RANBP9. Belongs to the calbindin family. Protein type: Calcium-binding. Chromosomal Location of Human Ortholog: 8q21.3. Cellular Component: cell soma; axon; dendrite; synapse; nucleus; cytosol. Molecular Function: vitamin D binding; protein binding; zinc ion binding; calcium ion binding. Biological Process: cytosolic calcium ion homeostasis; long-term memory; short-term memory; regulation of synaptic plasticity; locomotory behavior

size1 :

0.1 mg

price1 :

280 USD

more info or order :

MyBioSource product webpage