Anti-AVPR1A antibody | MyBioSource MBS176788 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-AVPR1A antibody

catalog :

MBS176788

quantity :

0.1 mg

price :

280 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

rat

application :

western blot

more info or order :

MyBioSource product webpage

image

image 1 :

Anti-AVPR1A antibody, MBS176788, All Western blotting. All lanes: Anti-AVPR1A(MBS176788) at 0.5ug/ml. Lane 1: Rat Liver Tissue Lysate at 40ug. Lane 2: Rat Kidney Tissue Lysate at 40ug. Predicted bind size: 47KD. Observed bind size: 47KD

product information

catalog number :

MBS176788

products type :

Antibody

products full name :

Anti-AVPR1A antibody

products short name :

[AVPR1A]

products name syn :

[Vasopressin V1a receptor; arginine vasopressin receptor 1A; Antidiuretic hormone receptor 1a antibody; Arginine vasopressin receptor 1A antibody; AVPR 1 antibody; AVPR 1A antibody; AVPR V1a antibody; AVPR1 antibody; AVPR1A antibody; SCCL vasopressin subtype 1a receptor antibody; V1 vascular vasopressin receptor AVPR1A antibody; V1a vasopressin receptor antibody; V1aR antibody; V1AR_HUMAN antibody; Vascular/hepatic type arginine vasopressin receptor antibody; Vascular/hepatic-type arginine vasopressin receptor antibody; Vasopressin V1a receptor antibody]

other names :

[Vasopressin V1a receptor; Vasopressin V1a receptor; vasopressin V1a receptor; antidiuretic hormone receptor 1a; arginine vasopressin receptor V1a; vascular/hepatic-type arginine vasopressin receptor; arginine vasopressin receptor 1A; AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor]

products gene name :

[AVPR1A]

other gene names :

[Avpr1a; Avpr1a; V1a; AVPR; V1aR; V1aR]

uniprot entry name :

V1AR_RAT

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Reacts with: Human, Rat. Predicted to work with: Mouse

sequence length :

424

specificity :

No cross reactivity with other proteins.

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB)

app notes :

Western Blot:. Concentration: 0.1-0.5ug/ml. Tested Species: Hu, Rat. Predicted Species: Ms. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

image1 heading :

Western Blot (WB)

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of rat AVPR1A (155-173aa HPLKTLQQPARRSRLMIAT), different from the related human and mouse sequences by one amino acid.

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for Vasopressin V1a receptor(AVPR1A) detection. Tested with WB in Human, Mouse, Rat. Background: Arginine vasopressin receptor 1A(officially called AVPR1A) is one of the three major receptor types for arginine vasopressin (AVPR1B and AVPR2 being the others). It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. This gene is mapped to 12q14.2. AVPR1A is present throughout the brain, as well as in the periphery, in the liver, kidney, and vasculature. The protein encoded by this gene acts as receptor for arginine vasopressin. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.

ncbi gi num :

108935913

ncbi acc num :

P30560.4

uniprot acc num :

P30560

ncbi mol weight :

47,655 Da

ncbi pathways :

Calcium Signaling Pathway (83442); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1010164); G Alpha (q) Signalling Events Pathway (1010197); GPCR Downstream Signaling Pathway (1010193); GPCR Ligand Binding Pathway (1010163); GPCRs, Class A Rhodopsin-like Pathway (198500); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1010213); Neuroactive Ligand-receptor Interaction Pathway (83445); Neuroactive Ligand-receptor Interaction Pathway (462)

ncbi summary :

This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues. [provided by RefSeq, Jul 2008]

uniprot summary :

AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1. Cellular Component: cytoplasmic vesicle membrane; integral to plasma membrane; integral to membrane; plasma membrane; cytoplasmic vesicle. Molecular Function: V1A vasopressin receptor binding; peptide hormone binding; vasopressin receptor activity. Biological Process: positive regulation of glutamate secretion; positive regulation of cellular pH reduction; positive regulation of systemic arterial blood pressure; cellular response to water deprivation; positive regulation of glycogen catabolic process; response to organic substance; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; response to corticosterone stimulus; penile erection; positive regulation of prostaglandin biosynthetic process; grooming behavior; response to inorganic substance; maternal behavior; calcium-mediated signaling; myotube differentiation; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; negative regulation of transmission of nerve impulse; regulation of adrenocorticotropin hormone secretion; positive regulation of vasoconstriction; sperm ejaculation; positive regulation of blood pressure

size1 :

0.1 mg

price1 :

280 USD

more info or order :

MyBioSource product webpage