catalog number :
MBS176240
products full name :
Anti-Aquaporin 9 antibody
products short name :
Aquaporin 9
products name syn :
Aquaporin-9; aquaporin 9; AQP 9 antibody; AQP-9 antibody; AQP9 antibody; AQP9_HUMAN antibody; Aquaglyceroporin-9 antibody; Aquaporin-9 antibody; Aquaporin9 antibody; HsT 17287 antibody; HsT17287 antibody; Small solute channel 1 antibody; SSC 1 antibody; SSC1 antibody
other names :
Aquaporin-9; Aquaporin-9; aquaporin-9; aquaglyceroporin-9; aquaporin 9; Aquaglyceroporin-9
products gene name :
AQP9
other gene names :
Aqp9; Aqp9; AQP-9; AI266899; 1700020I22Rik; AQP-9
uniprot entry name :
AQP9_MOUSE
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB)
app notes :
Western Blot (WB). Concentration: 0.1-0.5ug/ml. Tested Species: Ms. Predicted Species: n/a. Antigen Retrieval: n/a. Tested Species: In-house tested species with positive reults. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 9 (263-278aa VLFIQMHHSNPDPEVK).
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Aquaporin-9(AQP9) detection. Tested with WB in Mouse. Background: Aquaporin-9 is a protein that in humans is encoded by the AQP9 gene. AQP9 encodes a 295-amino-acid protein with the amino acid sequence identity with AQP3(48%), AQP7(45%), and other aquaporins(approximately 30%), suggesting that AQP3, AQP7, and AQP9 belong to a subfamily of the aquaporin family. AQP9 is the major glycerol channel in mouse erythrocytes and suggest that this transport pathway may contribute to the virulence of intraerythrocytic stages of malarial infection.
ncbi mol weight :
31,764 Da
ncbi pathways :
Aquaporin-mediated Transport Pathway (1001362); Bile Secretion Pathway (193148); Bile Secretion Pathway (193095); Passive Transport By Aquaporins Pathway (1001363); Transmembrane Transport Of Small Molecules Pathway (970706); Transport Of Glycerol From Adipocytes To The Liver By Aquaporins Pathway (1001365)
ncbi summary :
This gene encodes a member of the aquaglyceroporin subfamily of aquaporins. This protein transports water, glycerol, urea, purines and pyrimidines and plays a role in glycerol metabolism and osteoclast differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
uniprot summary :
AQP9: Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family. Protein type: Membrane protein, integral; Channel, misc.; Transporter, aquaporin family; Membrane protein, multi-pass; Transporter. Cellular Component: membrane; intracellular membrane-bound organelle; cell; integral to plasma membrane; basolateral plasma membrane; integral to membrane. Molecular Function: purine transmembrane transporter activity; pyrimidine transmembrane transporter activity; transporter activity; urea transmembrane transporter activity; water channel activity; glycerol channel activity. Biological Process: polyol transport; glycerol transport; cellular water homeostasis; nucleobase, nucleoside, nucleotide and nucleic acid transport; amine transport; cellular response to stress; water transport; purine transport; response to organic substance; response to mercury ion; transport; pyrimidine transport; canalicular bile acid transport; transmembrane transport