catalog number :
MBS176222
products full name :
Anti-CD134/OX40 antibody
products short name :
[CD134/OX40]
products name syn :
[Tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; ACT 35 antibody; ACT35 antibody; ACT35 antigen antibody; ATC35 antigen antibody; CD 134 antibody; CD134 antibody; CD134 antigen antibody; Lymphoid activation antigene ACT35 antibody; OX 40 antibody; OX40 antibody; OX40 antigen antibody; OX40 cell surface antigen antibody; OX40 homologue antibody; OX40L receptor antibody; TAX transcriptionally activated glycoprotein 1 receptor antibody; TAX transcriptionally-activated glycoprotein 1 receptor antibody; TNFRSF 4 antibody; TNFRSF4 antibody; TNR4_HUMAN antibody; Tumor necrosis factor receptor superfamily member 4 antibody; Txgp 1l antibody; Txgp1 antibody; Txgp1l antibody]
other names :
[Tumor necrosis factor receptor superfamily member 4; Tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily member 4; OX40 antigen; OX40L receptor; tax-transcriptionally activated glycoprotein 1; tumor necrosis factor receptor superfamily, member 4; OX40 antigen; OX40L receptor; CD_antigen: CD134]
products gene name :
[TNFRSF4]
other gene names :
[Tnfrsf4; Tnfrsf4; Ox40; ACT35; CD134; Ly-70; Txgp1; TXGP1L; Ox40; Txgp1]
uniprot entry name :
TNR4_MOUSE
specificity :
No cross reactivity with other proteins
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB)
app notes :
Western Blot :. Concentration: 0.1-0.5 ug/ml. Tested Species: Mouse. WB: The detection limit for TNFRSF4 is approximately 0.5ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse CD134 (22-43aa ARRLNCVKHTYPSGHKCCRECQ).
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 4(TNFRSF4) detection. Tested with WB in Mouse. Background: Tumor necrosis factor receptor superfamily, member4, also known as ACT35 or CD134 is a cell surface glycoprotein that was discovered through the production of a monoclonal antibody raised against the HUT-102 cell line. It belongs to the tumor necrosis factor receptor superfamily. CD134 was mapped to 1p36 by fluorescence in situ hybridization. CD134 is the primary receptor for feline immunodeficiency virus. CD134 expression can promote viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development.
ncbi mol weight :
30,154 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460)
uniprot summary :
TNFRSF4: Receptor for TNFSF4/OX40L/GP34. Protein type: Apoptosis; Receptor, misc.; Membrane protein, integral. Cellular Component: cell surface; membrane; plasma membrane; integral to membrane; external side of plasma membrane. Molecular Function: protein binding; tumor necrosis factor receptor activity. Biological Process: regulation of apoptosis; T cell proliferation; tumor necrosis factor-mediated signaling pathway; negative regulation of transcription factor activity; negative regulation of cytokine secretion; programmed cell death; positive regulation of B cell proliferation; cellular defense response; positive regulation of immunoglobulin secretion; negative regulation of transcription, DNA-dependent; regulation of protein kinase activity; inflammatory response