catalog number :
MBS176089
products full name :
Anti-Human Milk Fat Globule 1 antibody
products short name :
Milk Fat Globule 1
products name syn :
Lactadherin; milk fat globule-EGF factor 8 protein; BA 46 antibody; BA46 antibody; Breast epithelial antigen BA46 antibody; Contains Medin antibody; EDIL 1 antibody; EDIL1 antibody; HMFG antibody; hP47 antibody; HsT19888 antibody; Lactadherin antibody; Lactadherin precursor antibody; Medin antibody; MFG E8 antibody; MFG-E8 antibody; MFGE 8 antibody; MFGE8 antibody; MFGE8 protein antibody; MFGM antibody; MFGM_HUMAN antibody; Milk fat globule EGF factor 8 antibody; Milk fat globule EGF factor 8 protein antibody; Milk fat globule-EGF factor 8 antibody; O acetyl disialoganglioside synthase antibody; OAcGD3S antibody; SED1 antibody; SPAG10 antibody; Sperm associated antigen 10 antibody; Sperm surface protein hP47 antibody
other names :
Lactadherin; Lactadherin; lactadherin; medin; sperm surface protein hP47; sperm associated antigen 10; breast epithelial antigen BA46; O-acetyl disialoganglioside synthase; milk fat globule-EGF factor 8 protein; Breast epithelial antigen BA46; HMFG; MFGM; Milk fat globule-EGF factor 8; MFG-E8; SED1Cleaved into the following 2 chains:Lactadherin short form; Medin
products gene name :
MFGE8
other gene names :
MFGE8; MFGE8; BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG-E8; SPAG10; OAcGD3S; HsT19888; MFG-E8
uniprot entry name :
MFGM_HUMAN
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Human Milk Fat Globule 1 (165-180aa NGHEFDFIHDVNKKHK).
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Lactadherin(MFGE8) detection. Tested with WB, IHC-P in Human. Background: MFGE8(Milk Fat Globule-Egf Factor 8), also called as Lactadherin or SED1, is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. By fluorescence in situ hybridization, Collins et al.(1997) mapped the MFGE8 gene to chromosome 15q25. Hanayama et al.(2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes. MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. Bu et al.(2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay, they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon(PRKCE)-dependent mechanism.
ncbi mol weight :
37,523 Da
ncbi pathways :
Amyloids Pathway 366238!!Disease Pathway 530764!!Integrins In Angiogenesis Pathway 137999