catalog number :
MBS175764
products full name :
Anti-I-309 antibody
products short name :
I-309
products name syn :
C-C motif chemokine 1; chemokine(C-C motif) ligand 1; C-C motif chemokine 1 antibody; CCL1 antibody; CCL1_HUMAN antibody; Chemokine CC Motif Ligand 1 antibody; inflammatory cytokine I-309 antibody; P500 antibody; SCYA1 antibody; SISe antibody; small inducible cytokine A1 antibody; Small-inducible cytokine A1 antibody; T lymphocyte secreted protein I-309 antibody; T lymphocyte-secreted protein I-309 antibody; TCA3 antibody
other names :
C-C motif chemokine 1; C-C motif chemokine 1; C-C motif chemokine 1; inflammatory cytokine I-309; T lymphocyte-secreted protein I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3); chemokine (C-C motif) ligand 1; Small-inducible cytokine A1; T lymphocyte-secreted protein I-309
products gene name :
CCL1
other gene names :
CCL1; CCL1; P500; SISe; TCA3; I-309; SCYA1; SCYA1
uniprot entry name :
CCL1_HUMAN
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human I-309 (80-96aa WVQRHRKMLRHCPSKRK).
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for C-C motif chemokine 1(CCL1) detection. Tested with WB in Human. Background: CCL1, Chemokine(C-C motif) ligand 1, is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.
ncbi mol weight :
10,992 Da
ncbi pathways :
Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460)
ncbi summary :
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014]
uniprot summary :
CCL1: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. Belongs to the intercrine beta (chemokine CC) family. Protein type: Secreted; Secreted, signal peptide; Chemokine; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 17q12. Cellular Component: extracellular space. Molecular Function: chemokine activity. Biological Process: cellular calcium ion homeostasis; viral reproduction; immune response; chemotaxis; signal transduction