Anti-Connexin 43/GJA1 antibody | MyBioSource MBS175756 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-Connexin 43/GJA1 antibody

catalog :

MBS175756

quantity :

0.1 mg

price :

245 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

catalog number :

MBS175756

products type :

Antibody

products full name :

Anti-Connexin 43/GJA1 antibody

products short name :

Connexin 43/GJA1

products name syn :

Gap junction alpha-1 protein; gap junction protein, alpha 1, 43kDa; Connexin 43 antibody; Connexin-43 antibody; Connexin43 antibody; Cx 43 antibody; CX43 antibody; CXA1_HUMAN antibody; DFNB38 antibody; Gap junction 43 kDa heart protein antibody; Gap junction alpha 1 protein antibody; Gap junction alpha-1 protein antibody; Gap junction protein alpha 1 43kD antibody; Gap junction protein alpha 1 43kDa(connexin 43) antibody; Gap junction protein alpha 1 43kDa antibody; Gap junction protein alpha like antibody; GJA 1 antibody; Gja1 antibody; GJAL antibody; HGNC:4282 antibody; HGNC:8112 antibody; Oculodentodigital dysplasia antibody; ODD antibody; ODDD antibody; ODOD antibody; SDTY 3 antibody; SDTY3 antibody; Syndactyly type III antibody

other names :

Gap junction alpha-1 protein; Gap junction alpha-1 protein; gap junction alpha-1 protein; connexin 43; connexin-43; gap junction 43 kDa heart protein; gap junction protein, alpha 1, 43kDa; Connexin-43; Cx43; Gap junction 43 kDa heart protein

products gene name :

GJA1

other gene names :

GJA1; GJA1; HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1; GJAL; Cx43

uniprot entry name :

CXA1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

382

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 43 (366-382aa RASSRASSRPRPDDLEI), identical to the related rat and mouse sequences.

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for Gap junction alpha-1 protein(GJA1) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: Connexins 43(Cx43), also called GAP Junction Protein, alpha-1(GJA1). Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin43 gap-junction gene, which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia. Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.

ncbi gi num :

117706

ncbi acc num :

P17302.2

uniprot acc num :

P17302

ncbi mol weight :

43,008 Da

ncbi pathways :

Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Corticotropin-releasing Hormone Pathway 920957!!EGFR1 Signaling Pathway 198782!!Formation Of Annular Gap Junctions Pathway 105934!!Gap Junction Pathway 83072!!Gap Junction Pathway 483!!Gap Junction Assembly Pathway 105928

ncbi summary :

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]

size :

0.1 mg

price :

245 USD