antibody

Anti-Macrophage Inflammatory Protein 1 beta antibody

MBS175746

0.1 mg

245 USD

polyclonal

rabbit

nonconjugated

Antibody

Anti-Macrophage Inflammatory Protein 1 beta antibody

Macrophage Inflammatory Protein 1 beta

C-C motif chemokine 4; chemokine(C-C motif) ligand 4; MIP 1 beta antibody; Secreted protein G 26 antibody; ACT 2 antibody; ACT-2 antibody; ACT2 antibody; AT744.1 antibody; AT744.2 antibody; C C motif chemokine 4 antibody; C C motif chemokine 4 like antibody; CC chemokine ligand 4 antibody; CC chemokine ligand 4L1d2 antibody; CC chemokine ligand 4L2 antibody; CCL4 antibody; CCL4_HUMAN antibody; ccl4l 1 antibody; CCL4L antibody; CCL4L1 antibody; Chemokine(C C motif) ligand 4 antibody; Chemokine(C C motif) ligand 4 like 1 antibody; Chemokine(C C motif) ligand 4 like 1, telomeric antibody; Chemokine(C C motif) ligand 4 like 2 antibody; Chemokine CC Motif Ligand 4 antibody; G 26 antibody; G 26 T lymphocyte secreted protein antibody; G-26 T-lymphocyte-secreted protein antibody; HC21 antibody; LAG 1 antibody; LAG-1 antibody; LAG1 antibody; Lymphocyte activation gene 1 antibody; Lymphocyte activation gene 1 protein antibody; Macrophage inflammatory protein 1 beta antibody; Macrophage inflammatory protein 1-beta antibody; Macrophage inflammatory protein 1b2 antibody; MGC104418 antibody; MGC126025 antibody; MGC126026 antibody; MIP-1-beta antibody; MIP-1-beta(1-69) antibody; MIP-1-beta(3-69) antibody; MIP1 beta antibody; MIP1B antibody; MIP1B1 antibody; Monocyte adherence induced protein 5 alpha antibody; PAT 744 antibody; Protein H400 antibody; SCYA2 antibody; SCYA4 antibody; SCYA4L antibody; Secreted protein G26 antibody; SIS gamma antibody; SIS-gamma antibody; Small inducible cytokine A4(homologous to mouse Mip 1b) antibody; Small inducible cytokine A4 antibody; Small-inducible cytokine A4 antibody; T cell activation protein 2 antibody; T-cell activation protein 2 antibody

C-C motif chemokine 4; C-C motif chemokine 4; C-C motif chemokine 4; ACT2; SIS-gamma; MIP-1 beta; MIP-1-beta; immune activation protein 2; small inducible cytokine A4; small-inducible cytokine A4; macrophage inflammatory protein 1-beta; chemokine (C-C motif) ligand 4; Immune activation protein 2; ACT-2; ACT2; Macrophage inflammatory protein 1-beta; MIP-1-beta; Protein H400; SIS-gamma; Small-inducible cytokine A4

CCL4

Ccl4; Ccl4; Act-2; Mip1b; Scya4; MIP-1B; AT744.1; Mip1b; Scya4; ACT-2; ACT2; MIP-1-beta

CCL4_MOUSE

Polyclonal

IgG

Rabbit

Mouse

92

Immunogen affinity purified.

Lyophilized

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Western Blot (WB)

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Macrophage Inflammatory Protein 1 beta  (74-88aa CANPSEPWVTEYMSD).

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Description: Rabbit IgG polyclonal antibody for C-C motif chemokine 4(CCL4) detection. Tested with WB in Mouse. Background: Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize MIP-1-beta. Modi et al.(1991) assigned the SCYA4 gene to a slightly more distal location than had Irving et al.(1990): 17q21-q23 rather than 17q11-q21.

1346534

P14097.3

P14097

10,168 Da

Chemokine Receptors Bind Chemokines Pathway (1000944); Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (672435); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1000942); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Cytosolic DNA-sensing Pathway (125146); Cytosolic DNA-sensing Pathway (124833); GPCR Ligand Binding Pathway (1000941)

CCL4: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. Belongs to the intercrine beta (chemokine CC) family. Protein type: Secreted; Chemokine; Motility/polarity/chemotaxis; Secreted, signal peptide. Cellular Component: extracellular space; extracellular region. Molecular Function: identical protein binding; protein binding; CCR1 chemokine receptor binding; chemokine activity; cytokine activity; CCR5 chemokine receptor binding. Biological Process: leukocyte chemotaxis; response to toxin; immune response; positive regulation of calcium-mediated signaling; positive regulation of tumor necrosis factor production; inflammatory response; chemotaxis; positive regulation of calcium ion transport; positive regulation of vascular permeability

0.1 mg

245 USD