antibody

Anti-Caveolin-2 antibody

MBS175735

0.1 mg

245 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, immunohistochemistry, immunohistochemistry - paraffin section

Antibody

Anti-Caveolin-2 antibody

Caveolin-2

Caveolin-2; caveolin 2; CAV antibody; CAV2 antibody; CAV2_HUMAN antibody; Caveolae protein 20 kD antibody; Caveolin 2 antibody; Caveolin 2 isoform a and b antibody; Caveolin-2 antibody; MGC12294 antibody; OTTHUMP00000025032 antibody; OTTHUMP00000195982 antibody

Caveolin-2; Caveolin-2; caveolin-2; caveolae protein, 20-kD; caveolin 2 isoform a and b; caveolin 2

CAV2

CAV2; CAV2; CAV

CAV2_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

162

Immunogen affinity purified.

Lyophilized

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Caveolin-2 (1-17aa MGLETEKADVQLFMDDD), different from the related rat and mouse sequences by one amino acid.

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Description: Rabbit IgG polyclonal antibody for Caveolin-2(CAV2) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Caveolin-1 and caveolin-2 are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury. The CAV2 gene is mapped to 7q31.1-q31.2. The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons. The boundary of the last exon of CAV1 and CAV2 are analogous, suggesting that they arose through gene duplication. The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.

5915890

P51636.2

P51636

12,780 Da

Bacterial Invasion Of Epithelial Cells Pathway 149807!!Bacterial Invasion Of Epithelial Cells Pathway 148661!!EGFR1 Signaling Pathway 198782!!Endocytosis Pathway 102279!!Endocytosis Pathway 102181!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!Integrin-mediated Cell Adhesion Pathway 198816!!Proteoglycans In Cancer Pathway 782000

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011]

0.1 mg

245 USD