antibody

Anti-IL-8 antibody

MBS175692

0.1 mg

245 USD

polyclonal

rabbit

nonconjugated

western blot, immunohistochemistry, immunohistochemistry - paraffin section

Antibody

Anti-IL-8 antibody

IL-8

Interleukin-8(IL-8); interleukin 8; (Ala-IL-8)77 antibody; (Ser-IL-8)72 antibody; 3 10C antibody; 310C antibody; AMCF 1 antibody; AMCF1 antibody; b ENAP antibody; Bbeta thromboglobulin like protein antibody; Beta thromboglobulin like protein antibody; C-X-C motif chemokine 8 antibody; CXC chemokine ligand 8 antibody; CXCL 8 antibody; CXCL8 antibody; Emoctakin antibody; GCP 1 antibody; GCP-1 antibody; GCP/IL-8 protein I antibody; GCP/IL-8 protein II antibody; GCP/IL-8 protein III antibody; GCP/IL-8 protein IV antibody; GCP/IL-8 protein V antibody; GCP/IL-8 protein VI antibody; GCP1 antibody; Granulocyte chemotactic protein 1 antibody; IL 8 antibody; IL-8 antibody; IL-8(1-77) antibody; IL-8(9-77) antibody; IL8 antibody; IL8/NAP1 form I antibody; IL8/NAP1 form II antibody; IL8/NAP1 form III antibody; IL8/NAP1 form IV antibody; IL8/NAP1 form V antibody; IL8/NAP1 form VI antibody; IL8_HUMAN antibody; Inteleukin 8 antibody; Interleukin8 antibody; K 60 antibody; K60 antibody; LECT antibody; LUCT antibody; Lymphocyte derived neutrophil activating factor antibody; Lymphocyte-derived neutrophil-activating factor antibody; LYNAP antibody; MDNCF antibody; MDNCF-b antibody; MDNCF-c antibody; MONAP antibody; Monocyte derived neutrophil activating peptide antibody; Monocyte derived neutrophil activating protein antibody; Monocyte derived neutrophil chemotactic factor antibody; Monocyte-derived neutrophil chemotactic factor antibody; Monocyte-derived neutrophil-activating peptide antibody; NAF antibody; NAP 1 antibody; NAP-1 antibody; NAP1 antibody; Neutrophil activating factor antibody; Neutrophil activating peptide 1 antibody; Neutrophil activating protein 1 antibody; Neutrophil-activating factor antibody; Neutrophil-activating protein 1 antibody; Protein 3 10C antibody; Protein 3-10C antibody; SCYB 8 antibody; SCYB8 antibody; Small inducible cytokine subfamily B member 8 antibody; T cell chemotactic factor antibody; T-cell chemotactic factor antibody; TSG 1 antibody; TSG1 antibody

Interleukin-8; Interleukin-8; interleukin-8; emoctakin; interleukin 8; T-cell chemotactic factor; neutrophil-activating peptide 1; beta-thromboglobulin-like protein; granulocyte chemotactic protein 1; tumor necrosis factor-induced gene 1; alveolar macrophage chemotactic factor I; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; small inducible cytokine subfamily B, member 8; lymphocyte derived neutrophil activating peptide; lung giant cell carcinoma-derived chemotactic protein; beta endothelial cell-derived neutrophil activating peptide; chemokine (C-X-C motif) ligand 8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factorCleaved into the following 7 chains:MDNCF-aAlternative name(s):GCP/IL-8 protein IV; IL8/NAP1 form I

IL8

CXCL8; CXCL8; IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1; IL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF

IL8_HUMAN

Polyclonal

IgG

Rabbit

Human

99

No cross reactivity with other proteins.

Immunogen affinity purified.

Lyophilized

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Western Blot (WB):. Concentration: 0.1-0.5ug/ml. Tested Species: Hu. Predicted Species: - . Antigen Retrieval: - . Immunohistochemistry (Paraffin-embedded Section): . Concentration: 0.5-1ug/ml. Tested Species: Hu. Predicted Species: - . Antigen Retrieval: By Heat. Tested Species: In-house tested species with positive results. Predicted Species: Species prediceted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IL8 (77-95aa CLDPKENWVQRVVEKFLKR).

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Description: Rabbit IgG polyclonal antibody for Interleukin-8(IL8) detection. Tested with WB, IHC-P in Human. Background: Interleukin-8(IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene. Interleukin-8(IL8) is a member of the CXC chemokine family(Hull et al., 2001). IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. The genes for IL8 have been co-localized on a 335-kb genomic fragment.

124359

P10145.1

P10145

11,338 Da

ATF-2 Transcription Factor Network Pathway (138006); ATF4 Activates Genes Pathway (530772); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Bladder Cancer Pathway (83115); Bladder Cancer Pathway (527); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Cellular Senescence Pathway (905991); Cellular Responses To Stress Pathway (645258); Chagas Disease (American Trypanosomiasis) Pathway (147809)

The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]

IL8: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. Belongs to the intercrine alpha (chemokine CxC) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Cytokine; Secreted; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 4q13-q21. Cellular Component: extracellular space; extracellular region. Molecular Function: protein binding; chemokine activity; interleukin-8 receptor binding. Biological Process: regulation of cell adhesion; neutrophil chemotaxis; neutrophil activation; negative regulation of G-protein coupled receptor protein signaling pathway; unfolded protein response; calcium-mediated signaling; chemotaxis; signal transduction; regulation of retroviral genome replication; induction of positive chemotaxis; G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; response to molecule of bacterial origin; receptor internalization; immune response; angiogenesis; cell cycle arrest; cell motility; inflammatory response; embryonic gut development

0.1 mg

245 USD