Anti-PP2A antibody | MyBioSource MBS175641 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-PP2A antibody

catalog :

MBS175641

quantity :

0.1 mg

price :

245 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS175641

products type :

Antibody

products full name :

Anti-PP2A antibody

products short name :

PP2A

products name syn :

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(PP2A-alpha); protein phosphatase 2, catalytic subunit, alpha isozyme; PP2A alpha antibody; PP2A-alpha antibody; PP2AA_HUMAN antibody; PP2Aalpha antibody; PP2Ac antibody; PP2CA antibody; PP2Calpha antibody; PPP2CA antibody; Protein phosphatase 2(formerly 2A) catalytic subunit alpha isoform antibody; Protein phosphatase 2 catalytic subunit alpha isoform antibody; Protein phosphatase 2, catalytic subunit, alpha isozyme antibody; Protein phosphatase 2A catalytic subunit, alpha isoform antibody; Replication protein C antibody; RP C antibody; RP-C antibody; RPC antibody; Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody

other names :

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; replication protein C; protein phosphatase 2A catalytic subunit, alpha isoform; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, alpha isozyme; Replication protein C; RP-C

products gene name :

PPP2CA

other gene names :

PPP2CA; PPP2CA; RP-C; PP2Ac; PP2CA; PP2Calpha; PP2A-alpha; RP-C

uniprot entry name :

PP2AA_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

309

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PP2A (6-20aa FTKELDQWIEQLNEC), identical to the related rat and mouse sequences.

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(PPP2CA) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: The catalytic subunit of human protein phosphatase 2A(PPP2CA) encodes a 309-amino acid polypeptide.It is localized to chromosome 5. The gene(approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue(Leu309) of protein serine/threonine phosphatase 2A catalytic subunit(PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.

ncbi gi num :

54038809

ncbi acc num :

P67775.1

uniprot acc num :

P67775

ncbi mol weight :

29,735 Da

ncbi pathways :

AMER1 Mutants Destabilize The Destruction Complex Pathway 1016198!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway 1016193!!APC Truncation Mutants Have Impaired AXIN Binding Pathway 1016194!!AXIN Missense Mutants Destabilize The Destruction Complex Pathway 1016197!!AXIN Mutants Destabilize The Destruction Complex, Activating WNT Signaling Pathway 1016195!!Activated TLR4 Signalling Pathway 106400!!Adaptive Immune System Pathway 366160!!Adrenergic Signaling In Cardiomyocytes Pathway 908257

ncbi summary :

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

245 USD

more info or order :

MyBioSource product webpage