catalog number :
MBS175623
products full name :
Anti-IL-6 antibody
products short name :
IL-6
products name syn :
Interleukin-6(IL-6); interleukin 6(interferon, beta 2); Interleukin BSF 2 antibody; B cell differentiation factor antibody; B cell stimulatory factor 2 antibody; B-cell stimulatory factor 2 antibody; BSF 2 antibody; BSF-2 antibody; BSF2 antibody; CDF antibody; CTL differentiation factor antibody; Cytotoxic T cell differentiation factor antibody; Hepatocyte stimulating factor antibody; HGF antibody; HPGF antibody; HSF antibody; Hybridoma growth factor antibody; Hybridoma growth factor Interferon beta-2 antibody; Hybridoma plasmacytoma growth factor antibody; IFN-beta-2 antibody; IFNB2 antibody; IL 6 antibody; IL-6 antibody; IL6 antibody; IL6 protein antibody; Interferon beta 2 antibody; Interferon beta-2 antibody; Interleukin 6(interferon beta 2) antibody; Interleukin 6 antibody; Interleukin-6 antibody; Interleukin6 antibody
other names :
Interleukin-6; Interleukin-6; interleukin-6; IL-6; Interleukin 6 (interferon, beta 2); interleukin 6
other gene names :
Il6; Il6; ILg6; Ifnb2; Il-6; IL-6
uniprot entry name :
IL6_RAT
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat IL6 (195-211aa KALEEFLKVTMRSTRQT), different from the related mouse sequence by two amino acids.
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Interleukin-6(IL6) detection. Tested with WB in Mouse, Rat. Background: Interleukin-6(IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is one of the most important mediators of fever and of the acute phase response. IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Bowcock et al.(1988) assigned the IL6 gene to chromosome 7p21. By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al.(1988) mapped the IL6 gene to chromosome 7p15.
ncbi mol weight :
24,357 Da
ncbi pathways :
Adipogenesis Pathway (198479); African Trypanosomiasis Pathway (194377); African Trypanosomiasis Pathway (194323); Amoebiasis Pathway (167311); Amoebiasis Pathway (167191); Androgen Receptor Signaling Pathway (198529); Cellular Senescence Pathway (1010386); Cellular Responses To Stress Pathway (1010374); Chagas Disease (American Trypanosomiasis) Pathway (147806); Chagas Disease (American Trypanosomiasis) Pathway (147795)
ncbi summary :
a cytokine involved in development and possibly in neurodegenerative processes [RGD, Feb 2006]