catalog number :
MBS175612
products full name :
Anti-Surfactant Protein A antibody
products short name :
Surfactant Protein A
products name syn :
Pulmonary surfactant-associated protein A1(PSP-A/PSPA/SP-A/SP-A1); surfactant protein A1; 35 kDa pulmonary surfactant-associated protein antibody; Alveolar proteinosis protein antibody; COLEC4 antibody; Collectin 4 antibody; PSAP antibody; PSPA antibody; Pulmonary surfactant apoprotein antibody; Pulmonary surfactant-associated protein A1 antibody; SFTP1 antibody; SFTPA antibody; SFTPA1 antibody; SFTPA1B antibody; SP A antibody; SP A1 antibody
other names :
Pulmonary surfactant-associated protein A; Pulmonary surfactant-associated protein A; pulmonary surfactant-associated protein A; PSAP; PSP-A; surfactant pulmonary associated protein A1; surfactant associated protein A1
products gene name :
SFTPA1
other gene names :
Sftpa1; Sftpa1; SP-A; Sftp1; Sftp-1; Sftp-1; Sftp1; Sftpa; PSAP; PSP-A; SP-A
uniprot entry name :
SFTPA_MOUSE
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Surfactant Protein A (233-248aa WNDKGCLQYRLAICEF), identical to the related rat sequence.
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Pulmonary surfactant-associated protein A(SFTPA1) detection. Tested with WB, IHC-P in Mouse, Rat. Background: Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14. Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.
ncbi mol weight :
26,157 Da
ncbi pathways :
Pertussis Pathway (218112); Pertussis Pathway (218099); Phagosome Pathway (153914); Phagosome Pathway (153859)
uniprot summary :
SFTPA2: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Defects in SFTPA2 are a cause of pulmonary fibrosis idiopathic (IPF). Pulmonary fibrosis is a lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. It results in acute lung injury with subsequent scarring and endstage lung disease. Belongs to the SFTPA family. Protein type: Secreted, signal peptide; Secreted. Cellular Component: multivesicular body; extracellular space; rough endoplasmic reticulum; cytoplasmic vesicle. Biological Process: positive regulation of phagocytosis