product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Collagen IV antibody
catalog :
MBS175589
quantity :
0.1 mg
price :
245 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS175589
products type :
Antibody
products full name :
Anti-Collagen IV antibody
products short name :
Collagen IV
products name syn :
Collagen alpha-2(IV) chain; collagen, type IV, alpha 2; Arresten antibody; Canstatin antibody; CO4A1_HUMAN antibody; COL4A1 antibody; COL4A1 NC1 domain antibody; COL4A2 antibody; COL4A3 antibody; COL4A4 antibody; COL4A5 antibody; Collagen Alpha 1(IV) Chain antibody; Collagen Alpha 2(IV) Chain antibody; collagen alpha-1(IV) chain antibody; Collagen IV Alpha 1 Polypeptide antibody; Collagen IV Alpha 2 Polypeptide antibody; Collagen Of Basement Membrane Alpha 1 Chain antibody; Collagen Of Basement Membrane Alpha 2 Chain antibody; Collagen Type IV Alpha 1 antibody; Collagen Type IV Alpha 2 antibody; Collagen Type IV Alpha 3 antibody; Collagen Type IV Alpha 4 antibody; Collagen Type IV Alpha 5 antibody; DKFZp686I14213 antibody; FLJ22259 antibody
other names :
Collagen alpha-2(IV) chain; Collagen alpha-2(IV) chain; collagen alpha-2(IV) chain; collagen alpha-2(IV) chain; canstatin; collagen, type IV, alpha 2
products gene name :
COL4A2
other gene names :
COL4A2; COL4A2; ICH; POREN2
uniprot entry name :
CO4A2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
1712
purity :
Immunogen affinity purified.
form :
Lyophilized
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin, Immunocytochemistry ICC
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen IV (1697-1712aa LIRTHISRCQVCMKNL), identical to the related rat and mouse sequences.
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Collagen alpha-2(IV) chain(COL4A2) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat. Background: Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.
ncbi gi num :
143811377
ncbi acc num :
P08572.4
uniprot acc num :
P08572
ncbi mol weight :
167,553 Da
ncbi pathways :
Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway 730306!!Axon Guidance Pathway 105688!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Collagen Biosynthesis And Modifying Enzymes Pathway 645289!!Collagen Formation Pathway 645288!!Developmental Biology Pathway 477129!!ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479
ncbi summary :
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
245 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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