Anti-ADAMTS2 antibody | MyBioSource MBS175567 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-ADAMTS2 antibody

catalog :

MBS175567

quantity :

0.1 mg

price :

245 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS175567

products type :

Antibody

products full name :

Anti-ADAMTS2 antibody

products short name :

ADAMTS2

products name syn :

A disintegrin and metalloproteinase with thrombospondin motifs 2(ADAM-TS 2/ADAM-TS2/ADAMTS-2); ADAM metallopeptidase with thrombospondin type 1 motif, 2; A disintegrin and metalloproteinase with thrombospondin motifs 2 antibody; A disintegrin like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 2 antibody; ADAM metallopeptidase with thrombospondin type 1 motif 2 antibody; ADAM TS 2 antibody; ADAM TS2 antibody; ADAM-TS 2 antibody; ADAM-TS2 antibody; ADAMTS 3 antibody; ADAMTS-2 antibody; ADAMTS2 antibody; ATS2_HUMAN antibody; EC 3.4.24.14 antibody; EDS VIIB antibody; EDS VIIC antibody; hPCPNI antibody; NPI antibody; PC I NP antibody; PC I-NP antibody; PCINP antibody; PCPNI antibody; pNPI antibody; Procollagen I N proteinase antibody; Procollagen I N-proteinase antibody; Procollagen I/II amino propeptide processing enzyme antibody; Procollagen I/II amino propeptide-processing enzyme antibody; Procollagen N endopeptidase antibody; Procollagen N-endopeptidase antibody

other names :

A disintegrin and metalloproteinase with thrombospondin motifs 2; A disintegrin and metalloproteinase with thrombospondin motifs 2; A disintegrin and metalloproteinase with thrombospondin motifs 2; procollagen I N-proteinase; procollagen N-endopeptidase; procollagen I/II amino propeptide-processing enzyme; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; ADAM metallopeptidase with thrombospondin type 1 motif, 2; Procollagen I N-proteinase; PC I-NP; Procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase; pNPI

products gene name :

ADAMTS2

other gene names :

ADAMTS2; ADAMTS2; NPI; PNPI; PCINP; PCPNI; PCI-NP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAMTS-3; PCINP; PCPNI; ADAM-TS 2; ADAM-TS2; ADAMTS-2; PC I-NP; pNPI

uniprot entry name :

ATS2_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

1211

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS2 (1189-1204aa KTRNQRIQELIDEMRK), different from the related rat and mouse sequences by three amino acids.

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 2(ADAMTS2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat. Background: ADAMTS2, A disintegrin and metalloproteinase with thrombospondin motifs 2, also known as procollagen I N-proteinase(PC I-NP), is an enzyme that in humans is encoded by the ADAMTS2 gene. The ADAMTS2 gene contains 22 exons. The human ADAMTS2 gene is mapped to chromosome 5q23-q24 by analysis of somatic cell hybrids. ADAMTS2 is responsible for processing several types of procollagen proteins. Procollagens are the precursors of collagens, the proteins that add strength and support to many body tissues. Specifically, this enzyme clips a short chain of amino acids off one end of the procollagen. This clipping step is necessary for collagen molecules to function normally and assemble into fibrils outside cells.

ncbi gi num :

218511944

ncbi acc num :

O95450.2

uniprot acc num :

O95450

ncbi mol weight :

61,756 Da

ncbi pathways :

Collagen Biosynthesis And Modifying Enzymes Pathway 645289!!Collagen Formation Pathway 645288!!Extracellular Matrix Organization Pathway 576262!!Metabolism Of Proteins Pathway 106230!!O-glycosylation Of TSR Domain-containing Proteins Pathway 980460!!O-linked Glycosylation Pathway 980459!!Post-translational Protein Modification Pathway 161012

ncbi summary :

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]

size :

0.1 mg

price :

245 USD

more info or order :

MyBioSource product webpage