Anti-CD62L antibody | MyBioSource MBS175447 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-CD62L antibody

catalog :

MBS175447

quantity :

0.1 mg

price :

245 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS175447

products type :

Antibody

products full name :

Anti-CD62L antibody

products short name :

CD62L

products name syn :

L-selectin; selectin L; A.11 antibody; AI528707 antibody; CD62 antigen ligand antibody; CD62 antigen-like family member L antibody; CD62L antibody; gp90 MEL antibody; gp90-MEL antibody; hLHRc antibody; IgA nephropathy, susceptibility to, included antibody; L Selectin antibody; L-selectin antibody; LAM-1 antibody; LAM1 antibody; LECAM1 antibody; LEU8 antibody; Leukocyte adhesion molecule 1 antibody; Leukocyte surface antigen Leu-8 antibody; Leukocyte surface antigen Leu8 antibody; Leukocyte-endothelial cell adhesion molecule 1 antibody; LNHR antibody; LSEL antibody; Ly-22 antibody; Ly-m22 antibody; Lyam-1 antibody; LYAM1 antibody; LYAM1_HUMAN antibody; Lymph node homing receptor antibody; Lymphocyte adhesion molecule 1 antibody; Lymphocyte antigen 22 antibody; Lymphocyte surface MEL-14 antigen antibody; MEL-14 antibody; Pln homing receptor antibody; PLNHR antibody; Selectin L antibody; Selectin, lymphocyte antibody; SELL antibody; TQ1 antibody

other names :

L-selectin; L-selectin; L-selectin; LAM-1; LECAM1; lymphocyte antigen 22; lymph node homing receptor; leukocyte adhesion molecule 1; CD62 antigen-like family member L; lymphocyte surface MEL-14 antigen; leukocyte-endothelial cell adhesion molecule 1; selectin, lymphocyte; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; Lymphocyte antigen 22; Ly-22; Lymphocyte surface MEL-14 antigen; CD_antigen: CD62L

products gene name :

SELL

other gene names :

Sell; Sell; Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; AI528707; L-selectin; Lnhr; Ly-22; Ly22; LAM-1; LECAM1; Ly-22

uniprot entry name :

LYAM1_MOUSE

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Mouse, Rat

sequence length :

372

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB)

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse CD62L (125-141aa KEDCVEIYIKRERDSGK), identical to the related rat sequence.

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB in Mouse, Rat. Background: L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL(L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

ncbi gi num :

126179

ncbi acc num :

P18337.1

uniprot acc num :

P18337

ncbi mol weight :

42,288 Da

ncbi pathways :

Adaptive Immune System Pathway (971210); Cell Adhesion Molecules (CAMs) Pathway (83266); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (1001323); Hemostasis Pathway (1001295); Immune System Pathway (971216); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (1001205)

uniprot summary :

SELL: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. Belongs to the selectin/LECAM family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Cellular Component: cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane. Molecular Function: protein binding; protease binding; cell adhesion molecule binding; carbohydrate binding; glycolipid binding. Biological Process: regulation of apoptosis; cell adhesion; response to ATP

size1 :

0.1 mg

price1 :

245 USD

more info or order :

MyBioSource product webpage