catalog number :
MBS175442
products full name :
Anti-Kallikrein 5 antibody
products short name :
Kallikrein 5
products name syn :
Kallikrein related-peptidase 5/Protein Klk5; kallikrein-related peptidase 5; HK5 antibody; Kallikrein 5 antibody; Kallikrein L2 antibody; Kallikrein Like 2 antibody; Kallikrein like protein 2 antibody; Kallikrein related peptidase 5 antibody; Kallikrein-5 antibody; Kallikrein-like protein 2 antibody; Kallikrein5 antibody; KLK 5 antibody; KLK L2 antibody; KLK-L2 antibody; KLK5 antibody; KLK5_HUMAN antibody; KLKL 2 antibody; KLKL2 antibody; SCTE antibody; Stratum Corneum Tryptic Enzyme antibody; UNQ570/PRO1132 antibody
other names :
18-day embryo whole body cDNA, RIKEN full-length enriched library, clone:1110030O19 product:similar to Kallikrein 5; Kallikrein 1-related peptidase b5; Kallikrein 1-related peptidase b5
products gene name :
KLK5
uniprot entry name :
Q9D140_MOUSE
reactivity :
Mouse, Rat. No cross reactivity with other proteins.
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
app notes :
WB:. Concentration: 0.1-0.5ug/ml. Tested Species: Ms. IHC-P: . 0.5-1ug/ml. Tested Species: Rat. Concluded Species: Ms. Antigen Retrieval: By Heat. Other applications have not been tested. Optimal dilutions should be determined by end user.
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 5 (278-293aa NLCEFVKWIKDTMNSN), different from the related rat sequence by three amino acids.
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Kallikrein related-peptidase 5/Protein Klk5(KLK5) detection. Tested with WB, IHC-P in Mouse, Rat. Background: KLK5(Kallikrein-related peptidase 5), formerly known as stratum corneum tryptic enzyme(SCTE) or KLKL2, is a serine protease expressed in the epidermis. The KLK5 gene is one of the fifteen kallikrein subfamily members which is located on 19q13.41. KLK5 has been suggested to regulate cell shedding in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. The KLK5 gene contains 5 coding exons spanning 9.3. KLK5 expression is upregulated in a breast cancer cell line in the presence of estrogens and progestins and is associated with more aggressive forms of epithelial ovarian carcinoma.
ncbi mol weight :
31,908 Da
uniprot summary :
KLK5: May be involved in desquamation. Belongs to the peptidase S1 family. Kallikrein subfamily. Protein type: EC 3.4.21.-; Protease; Secreted; Secreted, signal peptide. Cellular Component: extracellular space. Molecular Function: peptidase activity; serine-type endopeptidase activity. Biological Process: positive regulation of antibacterial peptide production; positive regulation of G-protein coupled receptor protein signaling pathway