Anti-NCAM antibody | MyBioSource MBS175405 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-NCAM antibody

catalog :

MBS175405

quantity :

0.1 mg

price :

245 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

catalog number :

MBS175405

products type :

Antibody

products full name :

Anti-NCAM antibody

products short name :

NCAM

products name syn :

Neural cell adhesion molecule 1(N-CAM-1/NCAM-1); neural cell adhesion molecule 1; antigen recognized by monoclonal antibody 5.1H11 antibody; CD56 antibody; MSK 39 antibody; MSK39 antibody; N-CAM-1 antibody; NCAM 1 antibody; NCAM antibody; NCAM C antibody; NCAM-1 antibody; NCAM1 antibody; NCAM1_HUMAN antibody; NCAMC antibody; Neural cell adhesion molecule 1 antibody; Neural cell adhesion molecule NCAM antibody; OTTHUMP00000235666 antibody

other names :

Neural cell adhesion molecule 1; Neural cell adhesion molecule 1; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; antigen recognized by monoclonal antibody 5.1H11; neural cell adhesion molecule 1; CD_antigen: CD56

products gene name :

NCAM1

other gene names :

NCAM1; NCAM1; CD56; NCAM; MSK39; NCAM; N-CAM-1; NCAM-1

uniprot entry name :

NCAM1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

858

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human NCAM (657-673aa DHVMLKSLDWNAEYEVY), identical to the related rat and mouse sequences.

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for Neural cell adhesion molecule 1(NCAM1) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: NCAM is a membrane-bound glycoprotein that plays a role in cell-cell and cell-matrix adhesion through both its homophilic and heterophilic binding activity. The neural cell adhesion molecule appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis. Later in development it is found on various differentiated tissues and is a major CAM mediating adhesion among neurons and between neurons and muscle. NCAM gene is mapped to 11q23. The neural cell adhesion molecule(NCAM) can influence a number of diverse intercellular events, including junctional communication, the association of axons with pathways and targets, and signals that alter levels of neurotransmitter enzymes.

ncbi gi num :

205830665

ncbi acc num :

P13591.3

uniprot acc num :

P13591

ncbi mol weight :

40,760 Da

ncbi pathways :

Axon Guidance Pathway (105688); BDNF Signaling Pathway (712093); Cardiac Progenitor Differentiation Pathway (712094); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cytokine Signaling In Immune System Pathway (366171); Developmental Biology Pathway (477129); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); FGF Signaling Pathway (137989)

ncbi summary :

This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]

uniprot summary :

NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Cell adhesion. Chromosomal Location of Human Ortholog: 11q23.1. Cellular Component: Golgi membrane; cell surface; membrane; plasma membrane; integral to membrane; external side of plasma membrane. Molecular Function: identical protein binding. Biological Process: axon guidance; extracellular matrix organization and biogenesis; cytokine and chemokine mediated signaling pathway; cell adhesion

size1 :

0.1 mg

price1 :

245 USD