catalog number :
MBS175393
products full name :
Anti-Podoplanin/gp36 antibody
products short name :
Podoplanin/gp36
products name syn :
Podoplanin; podoplanin; AGGRUS antibody; GLYCOPROTEIN 36 KD antibody; Glycoprotein 36 antibody; gp 36 antibody; GP 38 antibody; GP 40 antibody; gp36 antibody; GP38 antibody; GP40 antibody; HT1A 1 antibody; HT1A1 antibody; hT1alpha1 antibody; hT1alpha2 antibody; Lung type I cell membrane associated glycoprotein antibody; Lung type I cell membrane associated glycoprotein isoform a antibody; Lung type I cell membrane associated glycoprotein T1A 2 antibody; OTS 8 antibody; OTS8 antibody; OTTHUMP00000009640 antibody; OTTHUMP00000044504 antibody; PA2.26 antibody; PA2.26 antigen antibody; PDPN antibody; PDPN_HUMAN antibody; Podoplanin antibody; PSEC0003 antibody; PSEC0025 antibody; T1 alpha antibody; T1 ALPHA GENE antibody; T1-alpha antibody; T1A 2 antibody; T1A antibody; TIA 2 antibody; TIA2 antibody
other names :
Podoplanin; Podoplanin; podoplanin; T1A; RTI140; glycoprotein 38; E11 antigen epitope; type I cell 40 kDa protein; epithelial cell surface transmembrane protein antigen; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; podoplanin; E11 antigen epitope; Glycoprotein 38; Gp38; OTS-8; RTI140; T1-alpha; T1A; Type I cell 40 kDa protein
products gene name :
PDPN
other gene names :
Pdpn; Pdpn; E11; Gp38; OTS-8; RTI40; T1-alpha; Gp38; Ots8; Gp38; T1A
uniprot entry name :
PDPN_RAT
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat Podoplanin/gp36 (155-166aa VVMRKISGRFSP), different from the related mouse sequence by one amino acid.
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Podoplanin(PDPN) detection. Tested with WB in Mouse, Rat. Background: PDPN(Podoplanin), also called T1A, T1A2, GP36, OTS8 or AGGRUS, is a protein that in humans is encoded by the PDPN gene. This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The PDPN gene is mapped to chromosome 1 by the International radiation Hybrid mapping consortium. The physiological function of PDPN may be related to its mucin-type character. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Immunohistochemical analysis of PDPN in placenta, kidney, lung, and nasal polyps showed expression at the apical plasma membrane of vascular endothelial cells and in alveolar epithelial cells. Overexpression of rat PDPN in human and rodent endothelial cells promoted formation of elongated cell extensions and significantly increased endothelial cell adhesion, migration, and tube formation. Inhibition of PDPN expression by small interfering RNAs decreased cell adhesion in cultured human dermal lymphatic endothelial cells.
ncbi mol weight :
17,579 Da
ncbi summary :
membrane glycoprotein that may function in lung development [RGD, Feb 2006]