catalog number :
MBS175353
products full name :
Anti-Estrogen Inducible Protein pS2 antibody
products short name :
Estrogen Inducible Protein pS2
products name syn :
Trefoil factor 1; trefoil factor 1; BCEI antibody; Breast cancer estrogen inducible protein antibody; Breast cancer estrogen inducible sequence antibody; Breast cancer estrogen-inducible protein antibody; D21S21 antibody; Gastrointestinal trefoil protein antibody; Gastrointestinal trefoil protein pS2 antibody; hP1.A antibody; HP1A antibody; HPS 2 antibody; HPS2 antibody; pNR 2 antibody; PNR-2 antibody; pNR2 antibody; Polypeptide P1.A antibody; Protein pS2 antibody; PS 2 antibody; pS2 antibody; pS2 protein antibody; TFF 1 antibody; TFF1 antibody; TFF1_HUMAN antibody; Trefoil factor 1 antibody
other names :
Trefoil factor 1; Trefoil factor 1; trefoil factor 1; protein pS2; trefoil factor 1; Protein pS2
products gene name :
TFF1
other gene names :
Tff1; Tff1; PS2; Bcei; Bcei; Ps2
uniprot entry name :
TFF1_MOUSE
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse Estrogen Inducible Protein pS2 (59-72aa CCFDDSVRGFPWCF), identical to the related rat sequence.
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Trefoil factor 1(TFF1) detection. Tested with WB, IHC-P in Mouse, Rat. Background: TFF1(Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
ncbi mol weight :
9,670 Da
uniprot summary :
TFF1: Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. Protein type: Secreted, signal peptide; Secreted. Cellular Component: extracellular space; cytoplasm; extracellular region. Molecular Function: protein binding; growth factor activity. Biological Process: negative regulation of cell proliferation; response to wounding; cell differentiation; response to estradiol stimulus