Polyclonal Anti-Chemokin (C-X3-C motif) ligand 1, Fractalkine/CX3L1 | MyBioSource MBS175324 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Anti-Chemokin (C-X3-C motif) ligand 1, Fractalkine/CX3L1

catalog :

MBS175324

quantity :

0.1 mg

price :

245 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS175324

products type :

Antibody

products full name :

Polyclonal Anti-Chemokin (C-X3-C motif) ligand 1, Fractalkine/CX3L1

products short name :

CX3CL1

products name syn :

Fractalkine; chemokine(C-X3-C motif) ligand 1; A 152E5.2 antibody; AB030188 antibody; ABCD 3 antibody; ABCD3 antibody; AI848747 antibody; C-X3-C motif chemokine 1 antibody; C3Xkine antibody; Chemokine(C-X3-C motif) ligand 1 antibody; Chemokine C X3 C motif ligand 1 antibody; Chemokine CX3C Motif Ligand 1 antibody; CX3C membrane anchored chemokine antibody; CX3C membrane-anchored chemokine antibody; CX3CL1 antibody; CXC 3 antibody; CXC3 antibody; CXC3C antibody; D8Bwg0439e antibody; FKN antibody; Fractalkine antibody; Neurotactin antibody; NTN antibody; NTT antibody; Processed fractalkine antibody; SCYD 1 antibody; SCYD1 antibody; Small inducible cytokine D1 antibody; Small inducible cytokine subfamily D(Cys X3 Cys) member 1 antibody; small inducible cytokine subfamily D(Cys-X3-Cys), member 1(fractalkine, neurotactin) antibody; Small inducible cytokine subfamily D member 1 antibody; Small-inducible cytokine D1 antibody; X3CL1_HUMAN antibody

other names :

Fractalkine; Fractalkine; fractalkine; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); chemokine (C-X3-C motif) ligand 1; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1Cleaved into the following chain:Processed fractalkine

products gene name :

CX3CL1

other gene names :

CX3CL1; CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin; FKN; NTT; SCYD1

uniprot entry name :

X3CL1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

397

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB)

app notes :

WB:. Concentration: 1ug/ml. Tested Species: Hu

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CX3CL1 (50-64aa HYQQNQASCGKRAII).

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for Fractalkine(CX3CL1) detection. Tested with WB in Human. Background: Chemokine(C-X3-C motif) ligand 1, also known as CX3CL1, is a large cytokine protein. It is said to be the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine(in humans) and neurotactin(in mice). Its gene is mapped to the long arm of chromosome 8. Being the large protein, it has got 373 amino acids. Imai et al.(1997) identified a 7-transmembrane high-affinity receptor(CX3CR1; 601470) for fractalkine and showed that it mediates both the adhesive and migratory functions of fractalkine.

ncbi gi num :

6175080

ncbi acc num :

P78423.1

uniprot acc num :

P78423

ncbi mol weight :

42,203 Da

ncbi pathways :

Chemokine Receptors Bind Chemokines Pathway (106359); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Direct P53 Effectors Pathway (137939); GPCR Ligand Binding Pathway (161020); Peptide Ligand-binding Receptors Pathway (106358); Signal Transduction Pathway (477114)

uniprot summary :

CX3CL1: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Belongs to the intercrine delta family. Protein type: Motility/polarity/chemotaxis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 16q13. Cellular Component: extracellular space; cell surface; integral to membrane; plasma membrane; extracellular region. Molecular Function: protein binding; chemokine activity; receptor binding. Biological Process: positive regulation of transforming growth factor-beta1 production; neutrophil chemotaxis; leukocyte chemotaxis; cytokine and chemokine mediated signaling pathway; defense response; chemotaxis; angiogenesis involved in wound healing; macrophage chemotaxis; leukocyte adhesive activation; positive regulation of angiogenesis; positive regulation of calcium-independent cell-cell adhesion; immune response; cell adhesion; lymphocyte chemotaxis; positive regulation of inflammatory response

size1 :

0.1 mg

price1 :

245 USD

more info or order :

MyBioSource product webpage