product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-INDOL1 antibody
catalog :
MBS175296
quantity :
0.1 mg
price :
245 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS175296
products type :
Antibody
products full name :
Anti-INDOL1 antibody
products short name :
INDOL1
products name syn :
ndoleamine 2,3-dioxygenase 2; indoleamine 2,3-dioxygenase 2; 3-dioxygenase 2 antibody; 3-dioxygenase-like protein 1 antibody; EC 1.13.11. antibody; I23O2_HUMAN antibody; IDO 2 antibody; IDO-2 antibody; Ido2 antibody; INDOL 1 antibody; Indoleamine 2 antibody; Indoleamine 2,3 dioxygenase 2 antibody; Indoleamine 2,3 dioxygenase like 1 protein antibody; Indoleamine 2,3 dioxygenase like protein 1 antibody; Indoleamine pyrrole 2,3 dioxygenase like 1 antibody; Indoleamine pyrrole 2,3 dioxygenase like protein 1 antibody; Indoleamine-pyrrole 2 antibody
other names :
Indoleamine 2,3-dioxygenase 2; Indoleamine 2,3-dioxygenase 2; indoleamine 2,3-dioxygenase 2; IDO-2; indoleamine 2,3-dioxygenase-like 1 protein; indoleamine 2,3-dioxygenase-like protein 1; indoleamine-pyrrole 2,3 dioxygenase-like 1; indoleamine-pyrrole 2,3-dioxygenase-like protein 1; indoleamine 2,3-dioxygenase 2; Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1
products gene name :
IDO2
other gene names :
IDO2; IDO2; INDOL1; INDOL1; IDO-2
uniprot entry name :
I23O2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
407
purity :
Immunogen affinity purified.
form :
Lyophilized
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human INDOL1 (1-20aa MLHFHYYDTSNKIMEPHRPN).
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Indoleamine 2,3-dioxygenase 2(IDO2) detection. Tested with WB in Human. Background: IDO2(Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer. The Gene Structure of the INDOL1 has 11 exons and spans 74 kb.
ncbi gi num :
215274147
ncbi acc num :
Q6ZQW0.3
uniprot acc num :
Q6ZQW0
ncbi mol weight :
19,610 Da
ncbi pathways :
African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Tryptophan Catabolism Pathway (106190); Tryptophan Metabolism Pathway (82964); Tryptophan Metabolism Pathway (332)
ncbi summary :
Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]
uniprot summary :
INDOL1: Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Belongs to the indoleamine 2,3-dioxygenase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Amino Acid Metabolism - tryptophan; Oxidoreductase; EC 1.13.11.-. Chromosomal Location of Human Ortholog: 8p11.21. Cellular Component: cytoplasm; cytosol. Molecular Function: metal ion binding; heme binding; indoleamine 2,3-dioxygenase activity; tryptophan 2,3-dioxygenase activity. Biological Process: tryptophan catabolic process to kynurenine; tryptophan catabolic process
size1 :
0.1 mg
price1 :
245 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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