Anti-IL12 p40 antibody | MyBioSource MBS175274 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-IL12 p40 antibody

catalog :

MBS175274

quantity :

0.1 mg

price :

245 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

catalog number :

MBS175274

products type :

Antibody

products full name :

Anti-IL12 p40 antibody

products short name :

IL12 p40

products name syn :

Interleukin-12 subunit beta(IL-12B); interleukin 12B(natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); 40 kD Subunit antibody; CLMF 2 antibody; CLMF antibody; CLMF p40 antibody; CLMF2 antibody; Cytotoxic lymphocyte maturation factor 2 antibody; Cytotoxic lymphocyte maturation factor 2 p40 antibody; Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody; HGNC:5970 antibody; IL 12 subunit p40 antibody; IL 12B antibody; IL-12 subunit p40 antibody; IL-12B antibody; IL12 subunit p40 antibody; IL12B antibody; IL12B_HUMAN antibody; Interleukin 12 beta chain antibody; Interleukin 12 p40 antibody; Interleukin 12 subunit beta antibody; Interleukin 12B antibody; Interleukin-12 subunit beta antibody; Natural killer cell stimulatory factor 2 antibody; NK cell stimulatory factor chain 2 antibody; NKSF 2 antibody; NKSF antibody; NKSF2 antibody; p40 antibody; TcMF antibody; TSF antibody

other names :

Interleukin-12 subunit beta; Interleukin-12 subunit beta; interleukin-12 subunit beta; CLMF p40; IL-12 subunit p40; IL12, subunit p40; interleukin 12, p40; interleukin-12 beta chain; NK cell stimulatory factor chain 2; cytotoxic lymphocyte maturation factor 40 kDa subunit; natural killer cell stimulatory factor, 40 kD subunit; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin 12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; NKSF2

products gene name :

IL12B

other gene names :

IL12B; IL12B; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B; NKSF2; IL-12B; CLMF p40; NKSF2

uniprot entry name :

IL12B_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

328

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB)

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human IL12 p40 (23-40aa IWELKKDVYVVELDWYPD).

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for Interleukin-12 subunit beta(IL12B) detection. Tested with WB in Human. Background: IL-12, Interleukin 12, heterodimerizes with the IL12 p35 subunit to form IL12 and with the IL23 p19 subunit to form IL23. IL12b p 40 exists as a monomer and as a homodimer. This gene encodes a subunit of Interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The IL-12b gene contains 8 exons, the first and last of which are noncoding. By PCR analysis of DNA from rodent/human cell hybrids containing intact chromosomes or translocation chromosomes, the IL-12b gene is mapped to 5q31-q33.This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

ncbi gi num :

266320

ncbi acc num :

P29460.1

uniprot acc num :

P29460

ncbi mol weight :

37,169 Da

ncbi pathways :

African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Allograft Rejection Pathway 920963!!Allograft Rejection Pathway 83123!!Allograft Rejection Pathway 535!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Chagas Disease (American Trypanosomiasis) Pathway 147809!!Chagas Disease (American Trypanosomiasis) Pathway 147795!!Cytokine-cytokine Receptor Interaction Pathway 83051

ncbi summary :

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

245 USD