catalog number :
MBS175269
products full name :
Anti-YB1 antibody
products short name :
YB1
products name syn :
Nuclease-sensitive element-binding protein 1; Y box binding protein 1; BP 8 antibody; CBF-A antibody; CCAAT binding transcription factor I subunit A antibody; CCAAT-binding transcription factor I subunit A antibody; CSDA2 antibody; CSDB antibody; DBPB antibody; DNA binding protein B antibody; DNA-binding protein B antibody; EFI-A antibody; Enhancer factor I subunit A antibody; MDR NF1 antibody; MGC104858 antibody; MGC110976 antibody; MGC117250 antibody; NSEP 1 antibody; NSEP1 antibody; Nuclease sensitive element binding protein 1 antibody; Nuclease-sensitive element-binding protein 1 antibody; p50 antibody; Q15905 antibody; Y-box binding protein 1 antibody; Y-box transcription factor antibody; Y-box-binding protein 1 antibody; YB 1 antibody; YB-1 antibody; YBOX1_HUMAN antibody; YBX 1 antibody; YBX1 antibody
other names :
Nuclease-sensitive element-binding protein 1; Nuclease-sensitive element-binding protein 1; nuclease-sensitive element-binding protein 1; CBF-A; EFI-A; DNA-binding protein B; Y-box-binding protein 1; Y-box transcription factor; enhancer factor I subunit A; nuclease sensitive element binding protein 1; CCAAT-binding transcription factor I subunit A; major histocompatibility complex, class II, Y box-binding protein I; Y box binding protein 1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1; YB-1
products gene name :
YBX1
other gene names :
YBX1; YBX1; YB1; BP-8; CSDB; DBPB; YB-1; CSDA2; NSEP1; NSEP-1; MDR-NF1; NSEP1; YB1; CBF-A; DBPB; EFI-A; YB-1
uniprot entry name :
YBOX1_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human YB1 (137-152aa KYAADRNHYRRYPRRR), identical to the related rat and mouse sequences.
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Nuclease-sensitive element-binding protein 1(YBX1) detection. Tested with WB in Human, Mouse, Rat. Background: YBX1(Y box binding protein 1), commonly referred to as "YB-1" by researchers, is a human protein. YB1 binding has an absolute requirement for the CCAAT box and relative specificity for the Y box. It has a molecular mass of 35,414 and contains 18% basic residues and putative nuclear localization signals. The YBX1 gene is mapped on 1p34.2. Ybx1 was highly expressed in mouse erythroid myeloid lymphoid clone-1(EML), a hematopoietic precursor cell line, but that it was downregulated in myeloid progenitors and in Gmcsf-treated EML cells during myeloid differentiation. Ybx1 was expressed at high levels in myeloid leukemic cells at different developmental stages. Knockdown of YBX1 in a human leukemic cell line inhibited proliferation ability, induced apoptosis, and induced megakaryocytic differentiation in response to arsenic trioxide treatment. YBX1 is downregulated during myeloid differentiation and aberrant YBX1 expression in leukemic cells may contribute to leukemia development by blocking differentiation.
ncbi mol weight :
35,924 Da
ncbi pathways :
BDNF Signaling Pathway 712093!!Gene Expression Pathway 105937!!Processing Of Capped Intron-Containing Pre-mRNA Pathway 160950!!SIDS Susceptibility Pathways 198901!!Signaling Events Mediated By PTP1B Pathway 138017!!MRNA Splicing Pathway 105951!!MRNA Splicing - Major Pathway 105952!!MRNA Processing Pathway 198843