product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Stra8 antibody
catalog :
MBS175253
quantity :
0.1 mg
price :
245 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS175253
products type :
Antibody
products full name :
Anti-Stra8 antibody
products short name :
Stra8
products name syn :
Stimulated by retinoic acid gene 8 protein homolog; stimulated by retinoic acid gene 8 homolog(mouse); stimulated by retinoic acid 8 homolog antibody; Stimulated by retinoic acid Gene 8 antibody; stimulated by retinoic acid gene 8 homolog antibody; Stimulated by retinoic acid gene 8 protein homolog antibody; STRA 8 antibody; STRA8 antibody; STRA8_HUMAN antibody
other names :
Stimulated by retinoic acid gene 8 protein homolog; Stimulated by retinoic acid gene 8 protein homolog; stimulated by retinoic acid gene 8 protein homolog; STRA8 {ECO:0000312 EMBL:AAP47163.1}; stimulated by retinoic acid 8 homolog; stimulated by retinoic acid gene 8 homolog; stimulated by retinoic acid 8
products gene name :
STRA8
other gene names :
STRA8; STRA8
uniprot entry name :
STRA8_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
330
specificity :
No cross reactivity with other proteins.
purity :
Immunogen affinity purified.
form :
Lyophilized
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Stra8 (313-330aa DEEMIMLQCTETFDDEDL).
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Stimulated by retinoic acid gene 8 protein homolog(STRA8) detection. Tested with WB in Human. Background: Stra8, stimulated by retinoic acid 8, is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid(RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying Stra8 expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.
ncbi gi num :
74713759
ncbi acc num :
Q7Z7C7.1
uniprot acc num :
Q7Z7C7
ncbi mol weight :
36,908 Da
ncbi summary :
This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010]
uniprot summary :
STRA8: Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase. Chromosomal Location of Human Ortholog: 7q33. Cellular Component: cytoplasm; nucleus. Molecular Function: protein dimerization activity. Biological Process: fertilization; meiotic cell cycle DNA replication checkpoint; ovarian follicle development; meiotic chromosome condensation; meiotic recombination; synapsis; meiotic DNA double-strand break formation; spermatogenesis; regulation of organ growth; female meiosis sister chromatid cohesion; DNA replication; oocyte development
size1 :
0.1 mg
price1 :
245 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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