antibody

Anti-mouse IL18 antibody

MBS175182

0.1 mg

280 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, enzyme immunoassay

Antibody

Anti-mouse IL18 antibody

IL18

Interleukin-18; interleukin 18(interferon-gamma-inducing factor); Iboctadekin antibody; IFN gamma inducing factor antibody; IFN-gamma-inducing factor antibody; IGIF antibody; IL 1 gamma antibody; IL 18 antibody; IL 1g antibody; IL-1 gamma antibody; IL-18 antibody; IL1 gamma antibody; IL18 antibody; IL18 protein antibody; IL1F4 antibody; IL1g antibody; IL1gamma antibody; ILIF4 antibody; Interferon gamma inducing factor antibody; Interferon gamma-inducing factor antibody; Interleukin 1 gamma antibody; Interleukin 18 antibody; Interleukin-1 gamma antibody; Interleukin-18 antibody; Interleukin18 antibody; MGC12320 antibody

Interleukin-18; Interleukin-18; interleukin-18; IL-1 gamma; interleukin-1 gamma; IFN-gamma-inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; interleukin 18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma

IL18

Il18; Il18; Igif; Il-18; Igif; IL-18; IFN-gamma-inducing factor; IL-1 gamma

IL18_MOUSE

Polyclonal

IgG

Rabbit

Mouse

192

Immunogen affinity purified.

Lyophilized

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Western Blot (WB), ELISA (EIA)

Western Blot (WB):. Recommended Concentration: 0.1-0.5ug/ml. Species: Mouse. ELISA:. Recommended Concentration: 0.1-0.5ug/ml . Species: Mouse

Immunogen: E Coli-derived mouse IL-18 recombinant protein (Position: N36-S192).

Contents: Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Description: Rabbit IgG polyclonal antibody for Interleukin-18(IL18) detection. Tested with WB, ELISA in Mouse. Background: Interleukin-18 also known as IL18 is a protein which in humans is encoded by the IL18 gene. The protein encoded by this gene is a proinflammatory cytokine.IL-18 is a cytokine produced by macrophages and other cells that belongs to the IL-1 superfamily. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide(LPS). After stimulation with IL-18, natural killer(NK) cells and certain T cells release another important cytokine called interferon-gamma(IFN-gamma) or type II interferon that plays an important role in activating the macrophages or other cells.The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. IL-18 binding protein(IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci.

3219810

P70380.2

P70380

22,135 Da

African Trypanosomiasis Pathway (194387); African Trypanosomiasis Pathway (194323); Cytokine Signaling In Immune System Pathway (970814); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Cytosolic DNA-sensing Pathway (125146); Cytosolic DNA-sensing Pathway (124833); Hypertrophy Model Pathway (198326); Immune System Pathway (971216); Inflammatory Bowel Disease (IBD) Pathway (842778)

IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family. Protein type: Cytokine. Cellular Component: extracellular space; apical plasma membrane; cytoplasm; extracellular region. Molecular Function: cytokine activity. Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of apoptosis; positive regulation of smooth muscle cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of NK T cell proliferation; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; positive regulation of smooth muscle cell migration; positive regulation of activated T cell proliferation; positive regulation of interleukin-8 production; positive regulation of superoxide release; positive regulation of neuron apoptosis; lipopolysaccharide-mediated signaling pathway; angiogenesis; inflammatory response; positive regulation of interleukin-17 production; regulation of cell adhesion; negative regulation of peptidyl-tyrosine phosphorylation; positive regulation of natural killer cell proliferation; T-helper 1 type immune response; MAPKKK cascade; interleukin-13 biosynthetic process; positive regulation of tumor necrosis factor production; sleep; positive regulation of chemokine production; positive regulation of vascular permeability; negative regulation of neutrophil apoptosis; detection of mechanical stimulus involved in sensory perception of pain; positive regulation of interferon-gamma production; induction of apoptosis via death domain receptors; response to hypoxia; interferon-gamma biosynthetic process; immune response; negative regulation of myoblast differentiation

0.1 mg

280 USD