Anti-Apolipoprotein A I antibody | MyBioSource MBS175176 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-Apolipoprotein A I antibody

catalog :

MBS175176

quantity :

0.1 mg

price :

245 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS175176

products type :

Antibody

products full name :

Anti-Apolipoprotein A I antibody

products short name :

Apolipoprotein A I

products name syn :

Apolipoprotein A-I(Apo-AI/ApoA-I); apolipoprotein A-I; Apo AI antibody; Apo-AI antibody; ApoA I antibody; ApoA-I antibody; APOA1 antibody; APOA1/APOC3 fusion gene antibody; APOA1_HUMAN antibody; Apolipoprotein A I precursor antibody; Apolipoprotein A-I(1-242) antibody; Apolipoprotein A1 antibody; Apolipoprotein AI antibody; Apolipoprotein of high density lipoprotein antibody; ApolipoproteinAI antibody; Brp14 antibody; Ltw1 antibody; Lvtw1 antibody; MGC117399 antibody; Sep1 antibody; Sep2 antibody

other names :

Apolipoprotein A-I; Apolipoprotein A-I; apolipoprotein A-I; apo-AI; apolipoprotein A-I; Apolipoprotein A1Cleaved into the following 2 chains:Proapolipoprotein A-I; ProapoA-I; Truncated apolipoprotein A-IAlternative name(s):Apolipoprotein A-I(1-242)

products gene name :

APOA1

other gene names :

APOA1; APOA1; Apo-AI; ApoA-I; ProapoA-I

uniprot entry name :

APOA1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

267

purity :

Immunogen affinity purified.

form :

Lyophilized

storage stability :

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

tested application :

Western Blot (WB)

other info1 :

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Apolipoprotein A I (42-58aa YVDVLKDSGRDYVSQFE), different from the related mouse and rat sequences by two amino acids.

other info2 :

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

products description :

Description: Rabbit IgG polyclonal antibody for Apolipoprotein A-I(APOA1) detection. Tested with WB in Human, Mouse, Rat. Background: Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase(LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I was also isolated as a prostacyclin(PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.

ncbi gi num :

113992

ncbi acc num :

P02647.1

uniprot acc num :

P02647

ncbi mol weight :

30,778 Da

ncbi pathways :

ABC-family Proteins Mediated Transport Pathway 106573!!ABCA Transporters In Lipid Homeostasis Pathway 477112!!African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Amyloids Pathway 366238!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Chylomicron-mediated Lipid Transport Pathway 106157!!Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911

ncbi summary :

This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

245 USD

more info or order :

MyBioSource product webpage