product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-CPAMD8 Antibody
catalog :
MBS1751524
quantity :
0.1 mg
price :
315 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1751524
products type :
Antibody
products full name :
Anti-CPAMD8 Antibody
products short name :
[CPAMD8]
products name syn :
[C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8; CPAMD8; KIAA1283; C3 and PZP like, alpha-2-macroglobulin domain containing 8]
other names :
[C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8; C3 and PZP like, alpha-2-macroglobulin domain containing 8]
products gene name :
[CPAMD8]
other gene names :
[CPAMD8; CPAMD8; VIP; ASGD8; K-CAP]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human; No cross reactivity with other proteins.
sequence length :
1,815
purity :
Immunogen Affinity Purified
form :
Lyophilized; Contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
storage stability :
Store at -20 degree C for one year. After reconstitution, store at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Direct ELISA (EIA)
app notes :
WB: 0.1-0.5ug/ml. IHC-P: 0.5-1ug/ml (Antigen Retrieval: By Heat). Direct ELISA: 0.1-0.5ug/ml. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal silutions should be determined by end users.
other info1 :
Immunogen: E Coli-derived human CPAMD8 recombinant protein (Position: R58-D234).
other info2 :
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500mug/ml. Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit for IHC(P).
products description :
CPAMD8 belongs to the complement component-3 (C3; 120700)/alpha-2-macroglobulin (A2M; 103950) family of proteins, which are involved in innate immunity and damage control. The encoded protein is membrane-associated and proteolytically processed to generate two chains. Mutations in this gene cause a form of anterior segment dysgenesis, a developmental disorder of the eye. By genomic sequence analysis, the CPAMD8 gene is mapped to chromosome 19p13.3-p13.2.
products references :
1. Cheong, S.-S., Hentschel, L., Davidson, A. E., Gerrelli, D., Davie, R., Rizzo, R., Pontikos, N., Plagnol, V., Moore, A. T., Sowden, J. C., Michaelides, M., Snead, M., Tuft, S. J., Hardcastle, A. J. Mutations in CPAMD8 cause a unique form of autosomal-recessive anterior segment dysgenesis. Am. J. Hum. Genet. 99: 1338-1352, 2016. 2. Li, Z.-F., Wu, X., Engvall, E. Identification and characterization of CPAMD8, a novel member of the complement 3/alpha-2-macroglobulin family with a C-terminal Kazal domain. Genomics 83: 1083-1093, 2004.
ncbi gi num :
259016204
ncbi acc num :
Q8IZJ3.2
uniprot acc num :
Q8IZJ3
ncbi summary :
This gene encodes a member of the protease inhibitor I39 (alpha-2-macroglobulin) family of proteins. These proteins are important in innate and acquired immunity. The encoded protein is membrane-associated and proteolytically processed to generate two chains. Mutations in this gene cause a form of anterior segment dysgenesis, a developmental disorder of the eye. [provided by RefSeq, May 2017]
size1 :
0.1 mg
price1 :
315 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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