catalog number :
MBS175122
products full name :
Anti-Aquaporin 5 antibody
products short name :
Aquaporin 5
products name syn :
Aquaporin-5(AQP-5); aquaporin 5; AQP 5 antibody; AQP-5 antibody; AQP5 antibody; AQP5_HUMAN antibody; Aquaporin 5 antibody; Aquaporin-5 antibody
other names :
Aquaporin-5; Aquaporin-5; aquaporin-5; AQP-5; aquaporin 5
products gene name :
AQP5
other gene names :
Aqp5; Aqp5; AQP-5
uniprot entry name :
AQP5_MOUSE
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse Aquaporin 5 (246-265aa EEDWEDHREERKKTIELTAH), identical to the related rat sequence.
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Aquaporin-5(AQP5) detection. Tested with WB, IHC-P in Mouse, Rat. Background: Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins(AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. At least five AQPs are expressed in the eye: AQP0(MIP) in lens fiber, AQP1 in cornea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in corneal and lacrimal gland epithelia. Among the seven human aquaporins cloned to date(AQPs 0-6), genes encoding the four most closely related aquaporins(AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions.
ncbi mol weight :
28,274 Da
ncbi pathways :
Aquaporin-mediated Transport Pathway (1001362); Passive Transport By Aquaporins Pathway (1001363); Salivary Secretion Pathway (153377); Salivary Secretion Pathway (153352); Transmembrane Transport Of Small Molecules Pathway (970706)
uniprot summary :
AQP5: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Belongs to the MIP/aquaporin (TC 1.A.8) family. Protein type: Transporter; Transporter, aquaporin family; Membrane protein, integral; Membrane protein, multi-pass; Channel, misc. Cellular Component: microvillus; membrane; endoplasmic reticulum; integral to plasma membrane; cell; apical plasma membrane; integral to membrane; plasma membrane; basal plasma membrane. Molecular Function: protein binding; transporter activity; water channel activity; glycerol channel activity. Biological Process: glycerol transport; camera-type eye morphogenesis; cellular water homeostasis; transport; carbon dioxide transport; cellular response to stress; water transport; transmembrane transport; saliva secretion