catalog number :
MBS175118
products full name :
Polyclonal Anti-SLC2A5 Antibody
products short name :
Glucose Transporter 5 GLUT5
products name syn :
Solute carrier family 2, facilitated glucose transporter member 5; solute carrier family 2(facilitated glucose/fructose transporter), member 5; Facilitated glucose transporter member 5 antibody; Fructose transporter antibody; glucose transporter like protein 5 antibody; Glucose transporter type 5 antibody; Glucose transporter type 5 small intestine antibody; GLUT 5 antibody; GLUT-5 antibody; GLUT5 antibody; GTR5_HUMAN antibody; SLC 2A5 antibody; SLC2A5 antibody; small intestine antibody; Solute carrier family 2 antibody
other names :
Solute carrier family 2, facilitated glucose transporter member 5; Solute carrier family 2, facilitated glucose transporter member 5; solute carrier family 2, facilitated glucose transporter member 5; GLUT-5; fructose transporter; glucose transporter type 5, small intestine; solute carrier family 2 (facilitated glucose transporter), member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5
products gene name :
SLC2A5
other gene names :
Slc2a5; Slc2a5; Glut5; Slc5a; AI526984; Glut5; GLUT-5
uniprot entry name :
GTR5_MOUSE
specificity :
No cross reactivity with other proteins.
purity :
Immunogen affinity purified.
storage stability :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
tested application :
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin
app notes :
Western Blot. Concentration: 0.1-0.5ug/ml. Tested Species: Ms, Rat. Predicted Species: -. Antigen Retrieval: -. Immunohistochemistry (Paraffin-embedded Section): . Concentration: 0.5-1ug/ml . Tested Species: Ms, Rat. Predicted Species: -. Antigen Retrieval: By Heat . Immunohistochemistry (Frozen Section): . Concentration: 0.5-1ug/mlTested Species: Rat . Predicted Species: Ms . Antigen Retrieval: -. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sects. Other applications have not been tested. Optimal dilutions should be determined by end users.
other info1 :
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse Glucose Transporter 5 GLUT5 (232-251aa ALQTLRGWKDVHLEMEEIRK), different from the related rat sequence by two amino acids.
other info2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
products description :
Description: Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 5(SLC2A5) detection. Tested with WB, IHC-P, IHC-F in Mouse, Rat. Background: GLUT5(Glucose transporter 5), also known as SLC2A5, is a fructose transporter expressed on the apical border of enterocytes in the small intestine. The GLUT5 gene is located on chromosome 1. GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal muscle, testis, kidney, fat tissue, and brain. Fructose malabsorption or Dietary Fructose Intolerance is a dietary disability of the small intestine, where the amount of fructose carrier in enterocytes is deficient. In humans the GLUT5 protein is encoded by the SLC2A5 gene.
ncbi pathways :
Carbohydrate Digestion And Absorption Pathway (170722); Carbohydrate Digestion And Absorption Pathway (170654); Class II GLUTs Pathway (1001345); Disease Pathway (970606); Facilitative Na+-independent Glucose Transporters Pathway (1001344); Glycogen Storage Diseases Pathway (970607); Glycolysis And Gluconeogenesis Pathway (198376); Hexose Transport Pathway (971436); Metabolism Pathway (971233); Metabolism Of Carbohydrates Pathway (971234)
uniprot summary :
GLUT5: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Plays an important role in fructose absorption by the intestine. Expressed primarily in the jejunal region of the small intestine. Expressed at low levels in human kidney, skeletal muscle, adipocytes, microglial cells and in the human blood-brain barrier. Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Transporter. Cellular Component: membrane; apical plasma membrane; integral to membrane; plasma membrane. Molecular Function: transporter activity; fructose transmembrane transporter activity; glucose transmembrane transporter activity; transmembrane transporter activity; substrate-specific transmembrane transporter activity. Biological Process: transport; fructose transport; carbohydrate transport; glucose transport; transmembrane transport