antibody

Anti-Cytokeratin Peptide 18 antibody (monoclonal)

MBS175098

0.1 mg

245 USD

monoclonal

mouse

nonconjugated

CK-18

human, rat

western blot, immunohistochemistry, immunohistochemistry - paraffin section

Antibody

Anti-Cytokeratin Peptide 18 antibody (monoclonal)

Cytokeratin Peptide 18

Keratin, type I cytoskeletal 18; keratin 18; K18; Keratin-18; CK-18; Cytokeratin-18; CYK18; Cell proliferation-inducing gene 46 protein

Keratin, type I cytoskeletal 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; keratin 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18

KRT18

KRT18; KRT18; K18; CYK18; CYK18; CK-18; K18

K1C18_HUMAN

Monoclonal

IgG1

CK-18

Mouse

Human, Rat

430

Ascites

Lyophilized

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin

Immunogen: The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.

Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Description: Mouse IgG monoclonal antibody for Cytokeratin Peptide 18, keratin 18 (KRT18) detection. Tested with WB, IHC-P, IHC-F in Human, rat. No cross reactivity with other proteins. Uniprot ID: P05783. Background: Intermediate filaments(IFs) are a structurally related family of cellular proteins that appear to be intimately involved with the cytoskeleton. Human keratin 18(KRT18) and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. The KRT18 gene is 3,791 bp long and the keratin 18 protein is coded for by 7 exons. The K18 gene is 3791 bp in length and the K18 protein is coded for by seven exons. By Southern blotting using the genomic DNA PCR product, the gene for keratin 18 is assigned to chromosome 12. Mutation of human keratin 18 in association with cryptogenic cirrhosis.

125083

P05783.2

P05783

48,058 Da

Caspase Cascade In Apoptosis Pathway 137974!!EGFR1 Signaling Pathway 198782!!Pathogenic Escherichia Coli Infection Pathway 83103!!Pathogenic Escherichia Coli Infection Pathway 672459!!Pathogenic Escherichia Coli Infection Pathway 516

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

0.1 mg

245 USD