antibody

Anti-NCAM antibody (monoclonal)

MBS175049

0.1 mg

245 USD

monoclonal

mouse

nonconjugated

IML-43

human, rat

western blot, immunocytochemistry

Antibody

Anti-NCAM antibody (monoclonal)

NCAM

Neural cell adhesion molecule 1; neural cell adhesion molecule 1; CD56; MSK39; N-CAM-1; NCAM; ANTIGEN MSK39 IDENTIFIED BY MONOCLONAL ANTIBODY 5.1H11

Neural cell adhesion molecule 1; Neural cell adhesion molecule 1; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; antigen recognized by monoclonal antibody 5.1H11; neural cell adhesion molecule 1; CD_antigen: CD56

NCAM1

NCAM1; NCAM1; CD56; NCAM; MSK39; NCAM; N-CAM-1; NCAM-1

NCAM1_HUMAN

Monoclonal

IgG1

IML-43

Mouse

Human, Rat

858

Ascites

Lyophilized

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Western Blot (WB), Immunocytochemistry (ICC)

Immunogen: Growth cone enriched plasma membrane fraction from E17 rat forebrain.

Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Description: Mouse IgG monoclonal antibody for NCAM, neural cell adhesion molecule 1 (NCAM1) detection. Tested with WB, ICC in Human, rat. No cross reactivity with other proteins. Uniprot ID: P13591. Background: The neural cell adhesion molecule appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis. Later in development it is found on various differentiated tissues and is a major CAM mediating adhesion among neurons and between neurons and muscle. NCAM shares many features with immunoglobulins and is considered a member of the immunoglobulin superfamily NCAM gene is mapped to 11q23.1.

205830665

P13591.3

P13591

40,760 Da

Axon Guidance Pathway (105688); BDNF Signaling Pathway (712093); Cardiac Progenitor Differentiation Pathway (712094); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cytokine Signaling In Immune System Pathway (366171); Developmental Biology Pathway (477129); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); FGF Signaling Pathway (137989)

This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]

NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Cell adhesion; Membrane protein, GPI anchor; Membrane protein, integral. Chromosomal Location of Human Ortholog: 11q23.1. Cellular Component: Golgi membrane; cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane. Molecular Function: identical protein binding. Biological Process: axon guidance; extracellular matrix organization and biogenesis; cytokine and chemokine mediated signaling pathway; cell adhesion

0.1 mg

245 USD