catalog number :
MBS173382
products full name :
Myoglobin (Mb), Porcine Heart
products short name :
Myoglobin
products name syn :
Mb; Myoglobin (Mb), Porcine
other names :
myoglobin; Myoglobin; myoglobin; myoglobin
other gene names :
MB; MB; PVALB; myoglobgin
uniprot entry name :
MYG_HUMAN
purity :
>= 95% (SDS-PAGE)
form :
Solution in 50% glycerol, 75mM Sodium chloride, 5mM sodium phosphate, and 0.05% sodium azide, pH7.2
storage stability :
At -20 degree C. Note: Avoid temperatures below -20 degree C. Shipping: Cold packs
other info1 :
Source: Porcine Heart. Appearance: Clear, reddish-brown solution. Protein: 1.6 mg/ml (E 1mg/ml 280nm =0.82)
other info2 :
Recertification: 2 years
products categories :
Proteins; Antigens; Standards/controls; Native Proteins; Myoglobin (mb)
products description :
MyBioSource sells porcine heart Myoglobin for research and diagnostic uses. Custom preparations, technical support, bulk quantities and aliquoting available. Porcine Myoglobin is found in skeletal and cardiac muscle cells and is capable of reversibly binding molecular oxygen and enhancing the rate of oxygen diffusion through the muscle cell. Myoglobin is an oxygen carrier in the cytoplasm and appears to be responsible for the transport of oxygen from the cell membrane to the mitochondrion. Myoglobin (Mb) is a Haem containing protein and implicated as a cause of acute renal failure following damage to muscle tissue (e.g. rhabdomyolysis, severe crush trauma, malignant hyperthermia, status epilepticus and neuroleptic malignant syndrome), due to its toxicity to renal tubular epithelium.
ncbi acc num :
NP_976311.1
ncbi gb acc num :
NM_203377.1
ncbi pathways :
Effects Of Nitric Oxide Pathway (920994)
ncbi summary :
This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
uniprot summary :
MB: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Belongs to the globin family. Protein type: Carrier. Chromosomal Location of Human Ortholog: 22q13.1. Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity. Biological Process: slow-twitch skeletal muscle fiber contraction; response to hydrogen peroxide; oxygen transport; heart development; response to hypoxia; response to hormone stimulus; brown fat cell differentiation; enucleate erythrocyte differentiation