protein

Alpha-Fetoprotein (AFP), Human

MBS173373

0.1 mg

235 USD

Protein

Alpha-Fetoprotein (AFP), Human

Alpha-Fetoprotein

AFP; a-fetoprotein; alpha-1-fetoprotein; alpha-fetoglobulin; alpha-1-fetoprotein; Alpha-Fetoprotein (AFP), Human - >=99% (SDS-PAGE) - Lyophilized

alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha-fetoglobulin; alpha-1-fetoprotein; alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin

AFP

FETA; HPAFP

AFP; AFP; AFPD; FETA; HPAFP; HPAFP

FETA_HUMAN

609

>= 99% (SDS-PAGE)

Lyophilized

At -20 degree C

Western Blot (WB)

Source: Human Cord Serum

Recertification: 3 years. Protein: Reported mg protein/vial (A 280 , E 0.1% 280 nm =0.52)

Proteins; Antigens; Standards/controls; Native Proteins; Immunogen; Alpha-fetoprotein (afp)

MyBioSource is the leading supplier and producer of Human cord serum alpha-Fetoprotein (AFP) in research and bulk quantities. Custom preparations, technical support, bulk quantities and aliquoting available. Alpha Fetoprotein (AFP) is a protein that is normally only produced in the fetus during its development. AFP measurement during pregnancy has been useful to detect certain abnormalities specifically if high levels are found in amniotic fluid, can indicate a developmental defect in the baby, and is a valuable diagnostic tumor marker.

178236

AAB58754.1

P02771

69000

Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]

AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; cytoplasm. Molecular Function: metal ion binding. Biological Process: transport; progesterone metabolic process; ovulation from ovarian follicle. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of

0.1 mg

235 USD

1 mg

415

10 mg

2350