protein

C-Reactive Protein (CRP), Human Pleural Fluid

MBS173367

1 mg

190 USD

Protein

C-Reactive Protein (CRP), Human Pleural Fluid

C-Reactive

CRP; C-Reactive Protein (CRP), Human - >=99% (SDS-PAGE) - Lyophilized

C-reactive protein; C-reactive protein; C-reactive protein; pentraxin 1; C-reactive protein, pentraxin-related

CRP

RP11-419N10.4; PTX1

CRP; CRP; PTX1; PTX1

CRP_HUMAN

91

Inflamation

>= 99% (SDS-PAGE)

Lyophilized from 0.05M sodium citrate pH 6.5 with polyethylene glycol and trehalose. Appearance: White powder

At -20 degree C

Source: Human Pleural Fluid. UNSPSC Code: 51131904. Solubility: Clear, Colorless (1mg protein/mL tris buffered saline with 5mM calcium chloride, pH 8.0)

Recertification: 7-19-2016. Protein: 1mg/vial(E 0.1% 280nm =1.8). CAS Number: 9007-41-4. Reconstitution: Tris buffered saline with 5mM Calcium chloride, pH 8.0

Proteins; Antigens; Standards/controls; Native Proteins; Immunogen; C-reactive Protein (crp)

MyBioSource is a major supplier of C-Reactive Protein (CRP) for medical research and diagnostic manufacturing. C-Reactive Protein is purified using multiple affinity chromotagraphy steps. Custom preparations, technical support, bulk quantities and aliquoting available. C-Reactive Protein (CRP) is a pentameric serum protein belonging to the pentraxin family that is comprised of five identical ~ 23kDa subunits. CRP is a positive acute phase reactant, the levels of which increase modestly in humans in response to inflammation, tissue injury or disease. The acute phase response develops in a wide range of acute and chronic inflammatory conditions like bacterial, viral, or fungal infections; rheumatic and other inflammatory diseases; malignancy; and tissue injury or necrosis.

30224

CAA39671.1

P02741

10,415 Da

Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Selenium Pathway (198825)

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 1q23.2. Cellular Component: extracellular space; growth cone; extracellular region; filopodium. Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; cholesterol binding; virion binding; low-density lipoprotein binding; calcium ion binding. Biological Process: protein polymerization; wound healing; defense response to Gram-positive bacterium; response to ethanol; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; response to hypoxia; acute-phase response; opsonization; inflammatory response; complement activation, classical pathway; aging

1 mg

190 USD

5 mg

450