catalog number :
MBS173364
products full name :
Follicle Stimulating Hormone (FSH), Human Pituitary - High Purity
products short name :
[Follicle Stimulating Hormone]
products name syn :
[Follicle Stimulating Hormone (FSH), Native Human Hormone - >=95% (SDS-PAGE), FSH]
other names :
[follicle-stimulating hormone; Follitropin subunit beta; follitropin subunit beta; FSH-B; FSH-beta; follitropin beta chain; follitropin, beta chain; follicle-stimulating hormone beta subunit; follicle stimulating hormone, beta polypeptide; Follicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chain]
products gene name :
[FSH]
other gene names :
[FSHB; FSHB; FSH-B; FSH-beta]
uniprot entry name :
FSHB_HUMAN
host :
Human Pituitary Glands
purity :
?95% as determined by SDS-PAGE. Immunogen affinity purified
storage stability :
Store at 2-8°C. Note: Protect from moisture. Aliquot and freeze at -20°C after reconstitution. Shipping: Cold pack
other info1 :
Appearance: White, lyophilized powder. Handling: Handle as a potentially hazardous substance.
other info2 :
Reconstitution: Neutral pH buffer of choice. Avoid extreme high and low pH. Contaminants: All contaminants are nd IRP hMG)
products categories :
Proteins; Antigens; Standards/controls; Native Proteins; Follicle Stimulating Hormone (fsh)
products description :
MyBioSource produces Human Follicle Stimulating Hormone (FSH) for research and clinical diagnostic manufacuting assays. Technical support, bulk quantities and aliquoting available. FSH is a hormone found in humans and other animals and is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the body. FSH and Luteinizing hormone (LH) act synergistically in reproduction.
ncbi acc num :
AAA52476.1
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); FSH Signaling Pathway (672455); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Glycoprotein Hormones Pathway (160989); GnRH Signaling Pathway (83091); GnRH Signaling Pathway (502)
ncbi summary :
The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
uniprot summary :
FSHB: Stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle- stimulating hormone deficiency (IFSHD). Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. Belongs to the glycoprotein hormones subunit beta family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11p13. Cellular Component: cytoplasm; extracellular region. Molecular Function: follicle-stimulating hormone activity; protein binding; hormone activity. Biological Process: progesterone biosynthetic process; follicle-stimulating hormone signaling pathway; peptide hormone processing; female gamete generation; Sertoli cell proliferation; female pregnancy; signal transduction; cellular protein metabolic process; regulation of osteoclast differentiation; transforming growth factor beta receptor signaling pathway; positive regulation of cell proliferation; positive regulation of bone resorption; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell migration. Disease: Follicle-stimulating Hormone Deficiency, Isolated