protein

Prolactin (PRL), Human Pituitary - Standard Grade

MBS173338

0.1 mg

655 USD

Protein

Prolactin (PRL), Human Pituitary - Standard Grade

Prolactin

Luteotropic Hormone (LTH); PRL; Prolactin (PRL), Native Human Hormone - >=50% (SDS-PAGE)

prolactin; Prolactin; prolactin; decidual prolactin; prolactin

PRL; PRL; PRL

PRL_HUMAN

227

>= 50% (SDS-PAGE)

Lyophilized

At -20 degree C

Source: Human Pituitary Glands

Reconstitution: Neutral pH buffer of choice. Avoid extreme high and low pH. Recertification: 5 years. Protein: >= 0.5 mg/mg solid (Accubind ELISA). Contaminants: TSH: = 12 IU/mg (Immunoassay)

Proteins; Antigens; Standards/controls; Native Proteins; Prolactin (prl)

MyBioSource is a producer and supplier of human pituitary Prolactin for research and IVD manufacturing. Technical support, bulk quantities and custom buffers and aliquoting available. Prolactin is an integral member of the immunoneuroendocronology network and appears to have a role in pathogenesis of autoimmune diseases. Prolactin was discovered 80 years ago and is currently viewed by clinical endocrinologists as a hormone of pituitary origin, whose production is negatively controlled by dopamine, whose biological actions relate exclusively to lactation and reproductive functions, for which any genetic disorder is yet to be identified, and whose unique associated pathology is hyperprolactinemia, which is efficiently cured using dopamine agonists. REF: Endocrine Abstracts (2011) 26 MTE11. Prolactin levels may be ordered when a person has symptoms of a prolactinoma, such as unexplained headaches, visual impairment, and/or galactorrhea. Testing for prolactin may be ordered, along with other tests, when a woman is experiencing infertility or irregular menses or when a man has symptoms such as decreased libido, galactorrhea, or infertility. Prolactin levels are also often ordered in men as a follow-up to a low testosterone level.

254675133

NP_001157030.1

NM_001163558.2

23kDa

Amyloids Pathway (366238); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Disease Pathway (530764); ErbB4 Signaling Events Pathway (137991); Glucocorticoid Receptor Regulatory Network Pathway (138014); Growth Hormone Receptor Signaling Pathway (477128); Immune System Pathway (106386); Jak-STAT Signaling Pathway (83077)

This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]

prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family. Protein type: Motility/polarity/chemotaxis; Cytokine; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6p22.3. Cellular Component: extracellular region. Molecular Function: protein binding; prolactin receptor binding; hormone activity. Biological Process: lactation; cell proliferation; cell surface receptor linked signal transduction; regulation of multicellular organism growth; positive regulation of JAK-STAT cascade; female pregnancy

0.1 mg

655 USD