catalog number :
MBS173332
products full name :
Cancer Antigen 125 (CA-125), Human
products short name :
[Cancer Antigen 125]
products name syn :
[CA-125; Carbohydrate Antigen 125; Mucin-16]
other names :
[Mucin-16; Mucin-16; mucin-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125; mucin 16, cell surface associated; Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125]
products gene name :
[MUC16]
other gene names :
[MUC16; MUC16; CA125; CA125; MUC-16; CA-125]
uniprot entry name :
MUC16_HUMAN
purity :
> 95% (SDS-PAGE)
form :
Solution in phosphate buffered saline pH 7.4 with 3% sucrose and 0.05% sodium azide
storage stability :
Store at -20°C. Avoid freeze/thaws. Shipping: Ships with Dry Ice.
other info1 :
Source: Human Ascites Fluid,adenocarcinoma . Appearance: Clear and colorless. Activity: 380 kU/mL (EIA)
other info2 :
Handling: Handle as a potentially hazardous substance. Recovery: Microfuge the vial before drawing from container.
products categories :
Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Cancer Antigen 125 (ca-125; Muc16)
products description :
MyBioSource is the leading supplier of Cancer Antigen 125 (CA-125, MUCIN 16) for ovarian cancer research and biomarkers for manufacturing. Custom preparations, technical support, bulk quantities and aliquoting available. Cancer Antigen 125 (CA125) is a surface antigen associated with epithelial ovarian cancer. In serum, CA125 is associated with a high molecular weight glycoprotein. Published studies have indicated that elevated serum CA125 levels can be found in individuals with serious endometroid, clear-cell and undifferentiated ovarian carcinoma. Associated Cancer Types: Ovarian Cancer Endometrial Cancer Fallopian Tube Cancer Lung Cancer Breast Cancer Gastrointestinal Cancer
ncbi pathways :
Metabolism Of Proteins Pathway (106230); O-linked Glycosylation Pathway (1127679); O-linked Glycosylation Of Mucins Pathway (530747); Post-translational Protein Modification Pathway (161012); Termination Of O-glycan Biosynthesis Pathway (530748)
uniprot summary :
MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Protein type: Cell adhesion; Membrane protein, peripheral; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; plasma membrane; integral to membrane; vesicle. Molecular Function: protein binding. Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; cell adhesion; post-translational protein modification