product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Alkaline Phosphatase (ALP), Human Placental
catalog :
MBS173241
quantity :
250 Units
price :
1230 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS173241
products type :
Protein
products full name :
Alkaline Phosphatase (ALP), Human Placental
products short name :
Alkaline Phosphatase
products name syn :
PLAP; Alkaline Phosphatase (ALP, PLAP), Human Placental - >=98% (SDS-PAGE)
other names :
alkaline phosphatase; Alkaline phosphatase, tissue-nonspecific isozyme; alkaline phosphatase, tissue-nonspecific isozyme; glycerophosphatase; tissue-nonspecific ALP; alkaline phosphomonoesterase; liver/bone/kidney-type alkaline phosphatase; alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase, liver/bone/kidney; Alkaline phosphatase liver/bone/kidney isozyme
products gene name :
ALP
other gene names :
ALPL; ALPL; HOPS; TNAP; APTNAP; TNSALP; AP-TNAP; AP-TNAP; TNSALP
uniprot entry name :
PPBT_HUMAN
sequence length :
524
specificity :
Tumor Marker, seminoma, ovarian cancer
purity :
>= 98% (SDS-PAGE)
form :
Lyophilized
storage stability :
At -20 degree C
other info1 :
Source: Human Placenta. EC Number: 3.1.3.1. UNSPSC Code: 12352204. Unit Definition: One unit will catalyze the hydrolysis of one micromole of p-nitrophenylphosphate to p-nitrophenol and phosphate per minute at 37 degree C at pH 10.4.
other info2 :
Recertification: 2 years. Protein: >= 0.5 mg protein/mg (Coomassie). CAS Number: 9001-78-9
products categories :
Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Immunogen; Alkaline Phosphatase (alp/plap)
products description :
MyBioSource produces Human Placental Alkaline Phosphatase (ALP) for medical research and diagnostic manufacturing uses. Custom preparations, technical support, bulk quantities and aliquoting available. Alkaline Phosphatase is a hydrolase enzyme responsible for removing phosphate groups in the 5- and 3- positions from many types of molecules, including nucleotides, proteins, and alkaloids. In humans, alkaline phosphatase is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. The optimal pH for the enzyme activity is pH=10 in standard conditions.
ncbi gi num :
178462
ncbi acc num :
AAB59378.1
ncbi mol weight :
51,045 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!BDNF Signaling Pathway 712093!!Endochondral Ossification Pathway 198812!!Folate Biosynthesis Pathway 83018!!Folate Biosynthesis Pathway 404!!Metabolic Pathways 132956!!TNF-alpha/NF-kB Signaling Pathway 198884
ncbi summary :
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
size :
250 Units
price :
1230 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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