catalog number :
MBS173200
products full name :
Troponin I (Tn-I), Human Heart
products short name :
Troponin I
products name syn :
Troponin I (Tn-I), Human Heart - >=98% (SDS-PAGE)
other names :
troponin I; troponin I
products gene name :
Tn-I
products gene name syn :
hTn-I
other gene names :
LOC100136571
purity :
>= 98% (SDS-PAGE)
concentration :
Protein Concentration: >= 0.5 mg/mL (A280)
storage stability :
At -20 degree C
other info1 :
Source: Human Heart. UNSPSC Code: 51131907
other info2 :
Recertification: 2 years. pH: 7.4 +/- 0.1. CAS Number: 77108-40-8
products categories :
Proteins; Antigens; Standards/controls; Native Proteins; Immunogen; Troponin I (tn-i)
products description :
MyBioSource produces Human Heart Troponin I (Tn-I) for research and manufacturing uses. Custom preparations, technical support, bulk quantities and aliquoting available. Current studies show that Troponin I is a part of the troponin complex. Troponin I binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. Human Troponin is a family of proteins (Troponin I, T and C) found in skeletal and heart muscle fibers; cardiac Troponin helps muscles contract. Certain subtypes of human troponin (cardiac troponin I and T) are very sensitive and specific indicators of damage to the heart muscle myocardium).
ncbi acc num :
NP_001117133.1
ncbi gb acc num :
NM_001123661.1
ncbi mol weight :
~24,000