catalog number :
MBS173195
products full name :
Holo Transferrin, Human Serum
products short name :
Holo Transferrin
products name syn :
Transferrin iron-saturated; Siderophilin; TRF; Holo TnF; Transferrin, Holo
other names :
trf; Trf; Trf
other gene names :
HAN_2g338
uniprot entry name :
A9BKI4_HEMAN
purity :
>= 98% (SDS-PAGE)
storage stability :
2-8 degree C
other info1 :
Source: Human Serum. Note: Heat treated at > 58 degree C for > 10 hours. Iron: 1,200 - 1,700 ppm. EC Number: 234-318-8. UNSPSC Code: 51131907
other info2 :
Recertification: 3 years. pH: 6.5 - 8.0 (3% solution). Iron Assay: 1,200 - 1,700 ppm. CAS Number: 11096-37-0
products categories :
Proteins; Antigens; Standards/controls; Native Proteins; Transferrin; Holo
products description :
MyBioSource is the leading supplier of Human Holo Transferrin from human serum, used for cell culture, medical research and manufacturing of clinical diagnostic assays for iron deficiencies and disorders of the immune system. Custom preparations, technical support, bulk quantities and aliquoting available. Purification procedures include selective size exclusion, ion exchange chromatography and gel fitration for transferrin products. Ultra Pure Human Holo Transferrin >99% pure available upon request. Human Transferrin is a plasma protein for iron ion delivery. Human Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron binding domains. Transferrin (TF) is related to other iron binding proteins including lactoferrin. When human transferrin loaded with iron encounters a transferrin receptor on the surface of a cell, it binds to it and is consequently transported into the cell in a vesicle. The cell will acidify the vesicle, causing human transferrin(TF) to release its iron ions. Each human transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+). Human Transferrin levels may be checked in iron deficiency, hemochromatosis and other iron overload disorders. Transferrin is also associated with the innate immune system. Human Transferrin is found in the mucosa and binds iron, thus creating an environment low in free iron, where few bacteria are able to survive.
ncbi acc num :
ABW98155.1