protein

Sex Hormone Binding Globulin (SHBG), Human Serum

MBS173187

0.1 mg

240 USD

Protein

Sex Hormone Binding Globulin (SHBG), Human Serum

Sex Hormone Binding Globulin

SHBG; Sex Hormone Binding Globulin (SHBG), Human Serum - >=90% (SDS-PAGE)

sex hormone-binding globulin isoform 1; Sex hormone-binding globulin; sex hormone-binding globulin; sex steroid-binding protein; testosterone-binding beta-globulin; testosterone-estrogen-binding globulin; testosterone-estradiol-binding globulin; testis-specific androgen-binding protein; sex hormone-binding globulin; Sex steroid-binding protein; SBP; Testis-specific androgen-binding protein; ABP; Testosterone-estradiol-binding globulin; TeBG; Testosterone-estrogen-binding globulin

SHBG

ABP; SBP; TEBG

SHBG; SHBG; ABP; SBP; TEBG; SHBG; SBP; ABP; TeBG

SHBG_HUMAN

402

>= 90% (SDS-PAGE, major band at 45kDa)

Lyophilized from 0.0M ammonium bicarbonante. May contain traces of buffer satls.

At -20 degree C (2-8 degree C Short-term). Note: Aliquot adn freeze at -20 degree C after reconsitution.

Source: Human Serum. Electrophoresis: One band with beta1 electrophoretic mobility. UNSPSC Code: 51131907. Appearance: White Powder. Protein: 0.1mg/vial (E 1mg/ml 280nm = 1.22). Electrophoresis: One band with beta1 electrophoretic mobility (Cellulose acetate electrophoresis)

Reconstitution: Phosphate buffered saline, pH >=7.0. Recertification: 5-11-2021. Note: Reconstitute into provided container and centrifuge to ensure full recovery.

Proteins; Antigens; Standards/controls; Native Proteins; Sex Hormone Binding Globulin (shbg)

MyBioSource sells Human Serum Sex Hormone Binding Globulin (SHBG) for research and diagnostic manufacturing purposes. Custom preparations, technical support, bulk quantities and aliquoting available. Sex hormone-binding globulin is a glycoprotein that binds to sex hormones, specifically testosterone and estradiol. Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin. Conditions with low SHBG include polycystic ovary syndrome, diabetes, and hypothyroidism. Conditions with high levels include pregnancy, hyperthyroidism, and anorexia nervosa.

7382460

NP_001031.2

NM_001040.4

~45,000

Nongenotropic Androgen Signaling Pathway (138048)

This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

SHBG: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: extracellular region. Molecular Function: androgen binding. Biological Process: primary spermatocyte growth

0.1 mg

240 USD

1 mg

1090