catalog number :
MBS173185
products full name :
Retinol Binding Protein (RBP), Human Urine
products short name :
Retinol Binding Protein
products name syn :
RBP; CRBP; Cellular retinol-binding protein; retinol-binding protein 1; Retinol Binding Protein (RBP), Human Urine - >=96% (SDS-PAGE)
other names :
retinol-binding protein 4; Retinol-binding protein 4; retinol-binding protein 4; RBP; PRBP; plasma retinol-binding protein; retinol binding protein 4, plasma; Plasma retinol-binding protein; PRBP; RBP
products gene name :
RBP1
products gene name syn :
CRBP1
other gene names :
Rbp4; Rbp4; RBPA; PRBP; RBP
uniprot entry name :
RET4_RAT
purity :
> = 96% (SDS-PAGE)
form :
Lyophilized from .02M NH 4 HCO 3 .May contain traces of buffer salts. Appearance: White powder
storage stability :
2-8 degree C
other info1 :
Source: Urine from patients with renal tubular proteinuria
other info2 :
Recertification: 6-3-2018. Protein: 1mg/vial (E 1mg/ml 280nm =1.94). Reconstitution: Use of a phosphate buffer, pH >7.0 containing 0.15M NaCl is recommended. Electrophoresis: One band with alpha 2 electrophoretic mobility.
products categories :
Proteins; Antigens; Standards/controls; Native Proteins; Retinol Binding Protein (rbp)
products description :
MyBioSource sells human urine Retinol Binding Protein (RBP) for research and diagnostic manufacturing purposes. Custom preparations, technical support, bulk quantities and aliquoting available. Retinol binding protein (RBP) is responsible for binding and transporting retinol (vitamin A). It has a binding site for one molecule of retinol and circulates in the plasma together with prealbumin in the form of a protein complex in a molar ratio of 1:1. This binding to prealbumin prevents greater glomerular losses of the human retinol-binding protein. Only the retinol-free form of the retinol-binding protein,which has no affinity for prealbumin, undergoes glomerular filtration unhindered as a result of its low molecular weight.
ncbi acc num :
NP_037294.1
ncbi gb acc num :
NM_013162.1
ncbi pathways :
Disease Pathway (1121849); Diseases Associated With Visual Transduction Pathway (1121888); Retinoid Cycle Disease Events Pathway (1121889); Retinoid Metabolism And Transport Pathway (1120793); Retinol Metabolism Pathway (219784); Signal Transduction Pathway (1120558); The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway (1120794); Visual Phototransduction Pathway (1120792)
ncbi summary :
may play a role in vitamin A transport [RGD, Feb 2006]
uniprot summary :
RBP1: Intracellular transport of retinol. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Chromosomal Location of Human Ortholog: 3q23. Cellular Component: cytosol. Molecular Function: retinoid binding; transporter activity; retinol binding; retinal binding. Biological Process: phototransduction, visible light; transport; retinoid metabolic process; vitamin A metabolic process