protein

Prealbumin/Transthyretin, Human Serum

MBS173178

1 mg

170 USD

Protein

Prealbumin/Transthyretin, Human Serum

Prealbumin

Transthyretin, Thyroxin Binding Prealbumin, TBPA

prealbumin; Lipocalin-1; lipocalin-1; VEG protein; tear prealbumin; Von Ebner gland protein; lipocalin 1 (tear prealbumin); protein migrating faster than albumin; lipocalin 1; Tear lipocalin; Tlc; Tear prealbumin; TP; Von Ebner gland protein; VEG protein

LCN1; LCN1; TP; TLC; PMFA; VEGP; VEGP; Tlc; TP; VEG protein

LCN1_HUMAN

176

>= 70% (SDS-PAGE)

Lyophilized powder from 0.02M NH4HCO3. May contain traces of buffer salts.

2-8 degree C

Source: Human Plasma

Reconstitution: Recommend using phosphate buffer, pH >7.0 with 0.15M NaCl. Advice: Reconstitute into provided container and centrifuge to ensure full recovery. Handling: Handle as a potentially hazardous substance. Recertification: 12-27-2017. CAS Number: 87090-18-4

Proteins; Antigens; Standards/controls; Native Proteins; Prealbumin (transthyretin; Ttr)

MyBioSource is the leading manufacturer of Standard Grade Human Plasma Prealbumin/Transthyretin. Custom preparations, technical support, bulk quantities and aliquoting available. Transthyretin (TTR) is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol. This is how transthyretin gained its name, transports thyroxine and retinol. Transthyretin was originally called prealbumin because it ran faster than albumins on electrophoresis gels prealbumin.

184458

AAA61845.1

Orphan Transporters Pathway (1127546); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Fatty Acids Pathway (187185); Transport Of Vitamins, Nucleosides, And Related Molecules Pathway (161075)

This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9. [provided by RefSeq, Nov 2011]

LCN1: Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. Belongs to the calycin superfamily. Lipocalin family. Protein type: Secreted; Secreted, signal peptide; Inhibitor. Chromosomal Location of Human Ortholog: 9q34. Cellular Component: extracellular space; extracellular region. Molecular Function: cysteine protease inhibitor activity. Biological Process: long-chain fatty acid transport; retinal homeostasis; sensory perception of taste; response to stimulus; proteolysis; transmembrane transport

1 mg

170 USD

10 mg

480

50 mg

1820