catalog number :
MBS173165
products full name :
Myoglobin (Mb), Human Heart
products short name :
Myoglobin
products name syn :
Myoglobin (Mb), Human Heart - >=99% (SDS-PAGE) - Liquid
other names :
myoglobin; Myoglobin; myoglobin; myoglobin
products gene name syn :
RP4-569D19.7; PVALB
other gene names :
MB; MB; PVALB; myoglobgin
uniprot entry name :
MYG_HUMAN
purity :
>= 99% (SDS-PAGE)
form :
Liquid. Appearance: Clear, reddish-brown solution
storage stability :
2-8 degree C
other info1 :
Source: Human Heart . UNSPSC Code: 51131907
other info2 :
Recertification: 3 years. Protein: 2.0 - 4.0 mg/mL (Lowry). CAS Number: 11080-17-4
products categories :
Proteins; Antigens; Standards/controls; Native Proteins; Immunogen; Myoglobin (mb)
products description :
MyBioSource produces human cardiac Myoglobin for research and manufacturing uses. Custom preparations, technical support, bulk quantities and aliquoting available. Single lot sizes from 1,000 - 5,000 mg. This product is a single-chain globular protein of 153 amino acids and contains a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. Myoglobin is found in skeletal and cardiac muscle cells and is capable of reversibly binding molecular oxygen and enhancing the rate of oxygen diffusion through the muscle cell. Human Myoglobin is an oxygen carrier in the cytoplasm and appears to be responsible for the transport of oxygen from the cell membrane to the mitochondrion. Myoglobin (Mb) is implicated as a cause of acute renal failure following damage to muscle tissue (e.g. rhabdomyolysis, severe crush trauma, malignant hyperthermia, status epilepticus and neuroleptic malignant syndrome), due to its toxicity to renal tubular epithelium.
ncbi acc num :
NP_976312.1
ncbi gb acc num :
NM_203378.1
ncbi mol weight :
Approx. 16.7 - 17.7 kDa
ncbi pathways :
Effects Of Nitric Oxide Pathway 920994
ncbi summary :
This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]