catalog number :
MBS173158
products full name :
Lysozyme, Human Neutrophils
products short name :
Lysozyme
products name syn :
Lysozyme, Human Neutrophils - >=95% (SDS-PAGE)
other names :
lysozyme; Lysozyme; lysozyme; 1,4-beta-N-acetylmuramidase; 1,4-beta-N-acetylmuramidase
products gene name syn :
LZM
other gene names :
Lzm; BmLys
uniprot entry name :
LYS_BOMMO
purity :
>= 95% (SDS-PAGE)
form :
Liquid. Appearance: Clear, colorless solution
storage stability :
At -20 degree C
other info1 :
Source: Human Neutrophils. EC Number: 3.2.1.17
other info2 :
Recertification: 1 year. Protein: 1.0 - 3.0 mg protein/mL (A280 E=2.5). CAS Number: 900-63-2
products categories :
Proteins; Antigens; Standards/controls; Native Proteins; Lysozyme
products description :
Custom preparations, technical support, bulk quantities and aliquoting available. Human Lysozyme is an enzyme commonly referred to as the "body's own antibiotic" since it kills bacteria. Human Lysozyme is a an enzyme that destroys bacterial cell walls by hydrolyzing the polysaccharide component of the cell wall. Human Lysozyme is abundantly present in a number of secretions, such as tears. Human Lysozyme is present in cytoplasmic granules of the polymorphonuclear neutrophils (PMN) and released through the mucosal secretions (such as tears and saliva). Clinical significance: Human Lysozyme levels in the blood are often increased in sarcoidosis. Lysozyme protects against bacterial infection by breaking down the carbohydrates in bacterial cell walls, killing them. Hence, lysozyme is part of the innate immune response. In saliva it protects the oral cavity from pathogens. In times of increased inflammation, such as during inflammation of the salivary glands or after a tonsillectomy, there is an increase in lysozyme. This protein also works in synergy with the bactericidal properties of lactoferrin, another common protein found in mucosal secretions. Lysozyme also has fungicidal properties, protecting mucosal areas from invasion by pathogenic yeast or fungi. Lysozyme has been shown to inhibit viral replication and infection such HIV. Lysozyme also interacts with and increases the function of histatin, a protein shown to be bactericidal and fungicidal.
ncbi acc num :
NP_001037448.1
ncbi gb acc num :
NM_001043983.1
ncbi mol weight :
~14,700