Lipase, Human Pancreas | MyBioSource MBS173153 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Lipase, Human Pancreas

catalog :

MBS173153

quantity :

10 Units

price :

200 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS173153

products type :

Protein

products full name :

Lipase, Human Pancreas

products short name :

Lipase

products name syn :

Pancreatic Triacylglycerol Lipase; PL; PTL; Pancreatic Lipase; Lipase, Human Pancreas - High Purity - Lyophilized

other names :

lipase; Gastric triacylglycerol lipase; gastric triacylglycerol lipase; gastric lipase; lipase, gastric

products gene name :

PNLIP

products gene name syn :

RP11-33D13.1; PL; PNLIPD; PTL

other gene names :

LIPF; LIPF; GL; HGL; HLAL; GL; Gastric lipase

uniprot entry name :

LIPG_HUMAN

sequence length :

398

purity :

Purified

form :

Lyophilized from tris chloride, pH 8.0, with sodium chloride, benzamidine and calcium chloride. Appearance: Tan powder

storage stability :

Aliquot and freeze at -20 degree C after reconstitution. Handling: Handle as a potentially hazardous substance. Storage Note: Protect from moisture. Shipping Note: Cold pack

other info1 :

Source: Human Pancreas. EC Number: 3.1.1.3. CAS Number: 9001-62-1. Solubility: Clear, colorless (1 mg/mL saline). Activity: 100 units/vial (Dimension® Clinical Chemistry System). Unit Definition: One unit will catalyze the hydrolysis of one micromole per minute of 1,2-o-dilauryl-rac-glycero-3-glutaric acid-(6’-methylresorufin) ester in the presence of co-lipase, bile salt, and calcium chloride at 37 degree C. Protein: 0.03 mg protein/vial (Coomassie). Specific Activity: 3,000 units/mg protein (Coomassie). Amylase: <0.01%. Protease: <0.01%. Ammonia: <0.01 micromole/vial

other info2 :

Declaration of Helsinki: All Donors provided signed Informed Consent in compliance with Declaration of Helsinki and filed with the appropriate agency/organization in the US. Advice: Reconstitute with tris buffered saline containing 1% BSA and 1 mM calcium chloride.

products categories :

Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Lipase

products description :

MyBioSource is the leading supplier of Human Pancreatic Lipase, for research and clinical diagnostic manufacturers. Custom preparations, technical support, bulk quantities and aliquoting available. Human Pancreatic lipase enzyme is a water-soluble enzyme that catalyzes the hydrolysis of ester bonds in water-insoluble, lipid substrates. Most lipases act at a specific position on the glycerol backbone of a lipid substrate (A1, A2 or A3). Human pancreatic lipase clinical significance: Investigations of pancreatic disorders, pancreatitis, acute and chronic renal disease.

ncbi gi num :

344242

ncbi acc num :

CAA00125.1

uniprot acc num :

P16233

ncbi mol weight :

48 kDa

ncbi pathways :

Acylglycerol Degradation Pathway (413388); Acylglycerol Degradation Pathway (468272); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Fatty Acid Beta Oxidation Pathway (198865); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Metabolic Pathways (132956); Triacylglyceride Synthesis Pathway (198859)

ncbi summary :

This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

uniprot summary :

PNLIP: a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]. Protein type: EC 3.1.1.3; Secreted, signal peptide; Secreted; Lipid Metabolism - glycerolipid; Hydrolase. Chromosomal Location of Human Ortholog: 10q26.1. Cellular Component: extracellular region. Molecular Function: triacylglycerol lipase activity; metal ion binding. Biological Process: phototransduction, visible light; cholesterol absorption; retinoid metabolic process; lipid digestion; lipid catabolic process. Disease: Pancreatic Lipase Deficiency

size1 :

10 Units

price1 :

200 USD

size2 :

100 Units

price2 :

360

size3 :

500 Units

price3 :

600

more info or order :

MyBioSource product webpage