product summary
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company name :
MyBioSource
product type :
protein
product name :
Eosinophil Peroxidase (EPO), Human
catalog :
MBS173121
quantity :
0.025 mg
price :
200 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS173121
products type :
Protein
products full name :
Eosinophil Peroxidase (EPO), Human
products short name :
Eosinophil Peroxidase
products name syn :
EPO; Eosinophil Peroxidase (EPO), Native Human - >=98% (SDS-PAGE)
other names :
eosinophil peroxidase preproprotein; Eosinophil peroxidase; eosinophil peroxidase; eosinophil peroxidase
products gene name :
EPX
other gene names :
EPX; EPX; EPO; EPP; EPXD; EPX-PEN; EPER; EPO; EPP; EPO
uniprot entry name :
PERE_HUMAN
sequence length :
715
purity :
> 98% (SDS-PAGE)
form :
0.2 micron filtered solution in 0.1M sodium phosphate with 0.4M sodium chloride, pH 7.5. Appearance: Clear, green to brown liquid
storage stability :
2-8 degree C. Do not freeze.
other info1 :
Source: Human Eosinophils. EC Number: 1.11.1.7. UNSPSC Code: 51131907. Unit Definition: One unit of eosinophil peroxidase will catalyze the consumption of one micromole of hydrogen peroxide and the production of 1/4 micromole of tetraguaiacol per minute at pH 7.0 and 25 degree C. Specific Activity: 1,500 U/mg protein
other info2 :
RZ Value: 0.89(A 280 /A 413 ). Recertification: 2 years. Protein: 1.2 mg protein/mL (Coomassie). CAS Number: 9003-99-0. Activity Enzymatic: 1,800 U/mL . Handling: Handle as a potentially hazardous substance. Recovery: Microfuge vial before drawing from container.
products categories :
Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Immunogen; Eosinophil Peroxidase (epo)
products description :
MyBioSource is the leading supplier of Human Eosinophil Peroxidase (EPO) for medical research and clinical diagnostic manufacturing. Custom preparations, technical support, bulk quantities and aliquoting available. Our observations show human Eosinophil peroxidase (EPO), is a dimer consisting of both heavy and light chain. Human Eosinophil peroxidase is a secreted hemoprotein that catalyzes oxidations of various substrates by hydrogen peroxide. Together with other leukocyte-derived enzymes, such as Myeloperoxidase, it plays an important role in the pathogenesis of asthma by mediating oxidative events that lead to the production of ROS (reactive oxygen species) and RNS (reactive nitrogen species).
ncbi gi num :
4503595
uniprot acc num :
P11678
ncbi mol weight :
77 kda (~53,000 mw heavy chain, ~13,000 mw light chain)
uniprot summary :
EPX: Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. Defects in EPX are the cause of eosinophil peroxidase deficiency (EPD). EPD is an autosomal recessive defect where anomalous eosinophils are characterized by nuclear hypersegmentation, hypogranulation, and negative peroxidase and phospholipid staining. Belongs to the peroxidase family. XPO subfamily. Protein type: Oxidoreductase; EC 1.11.1.7. Chromosomal Location of Human Ortholog: 17q23.1. Molecular Function: peroxidase activity; metal ion binding; heme binding. Biological Process: positive regulation of interleukin-4 production; negative regulation of interleukin-10 production; hydrogen peroxide catabolic process; negative regulation of interleukin-5 production; response to oxidative stress; defense response to nematode. Disease: Eosinophil Peroxidase Deficiency
size1 :
0.025 mg
price1 :
200 USD
size2 :
0.1 mg
price2 :
510
size3 :
0.5 mg
price3 :
1820
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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