protein

Haptoglobin, Bovine Serum

MBS173105

0.025 mg

290 USD

Protein

Haptoglobin, Bovine Serum

[Haptoglobin]

[Haptoglobin (Hp), Bovine]

[haptoglobin, partial; Haptoglobin-related protein; haptoglobin-related protein; Haptoglobin-related locus; haptoglobin-related protein]

[HPR; HPR; HP; A-259H10.2]

HPTR_HUMAN

91

> or = 90% (SDS-PAGE, bands at 10 and 40kDa indicative of alpha and beta subunits)

Frozen solution in phosphate buffered saline with 0.05% sodium azide

At -20 degree C. Avoid freeze/thaws. Shipping: Ships with dry ice

Source: Bovine acute phase serum

Protein: 0.93 mg/ml (E 1mg/ml 280nm =1.68. Note: Due to high affinity for hemoglobin, haptoglobin preparations unavoidably contain hemoglobin, which co-purifies during all chromatographic steps. Handling: Handle as a potentially hazardous substance. Recovery: Centrifuge briefly to ensure complete recovery. Mix thoroughly before sampling.

Proteins; Antigens; Standards/controls; Native Proteins; Haptoglobin (hp)

MyBioSource produces bovine serum Haptoglobin for research, life science, and manufacturing uses. Custom preparations, technical support, bulk quantities and aliquoting available. Haptoglobin can be used for the early diagnosis of bovine respiratory disease in cattle. Haptoglobin is a serum protein that consists of two alpha and two beta chains connected to disulfide bridges. The alpha and beta chains are characterized by molecular weights of 10kDa and 40kDa approximately, and acts as a hemoglobin scavenger and has been associated with protease inhibitory activity.

184321

AAA52686.1

623.65

African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Scavenging Of Heme From Plasma Pathway (771600)

This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]

HPR: a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 16q22.1. Cellular Component: extracellular region. Molecular Function: hemoglobin binding; catalytic activity. Biological Process: receptor-mediated endocytosis; metabolic process

0.025 mg

290 USD

0.1 mg

540

1 mg

1165